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RAT:DC1I2
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Dync1i2 (synonyms: Dnci2, Dncic2) | |
| Protein Name(s) | Cytoplasmic dynein 1 intermediate chain 2
Cytoplasmic dynein intermediate chain 2 Dynein intermediate chain 2, cytosolic DH IC-2 | |
| External Links | ||
| UniProt | Q62871 | |
| EMBL | U39044 U39045 U39046 | |
| UniGene | Rn.11014 | |
| PDB | 2PG1 | |
| PDBsum | 2PG1 | |
| ProteinModelPortal | Q62871 | |
| SMR | Q62871 | |
| BioGrid | 250544 | |
| DIP | DIP-36880N | |
| IntAct | Q62871 | |
| PhosphoSite | Q62871 | |
| PaxDb | Q62871 | |
| PRIDE | Q62871 | |
| UCSC | RGD:620174 | |
| RGD | 620174 | |
| eggNOG | NOG308180 | |
| HOGENOM | HOG000116383 | |
| HOVERGEN | HBG004083 | |
| InParanoid | Q62871 | |
| PhylomeDB | Q62871 | |
| EvolutionaryTrace | Q62871 | |
| NextBio | 619443 | |
| PRO | PR:Q62871 | |
| Proteomes | UP000002494 | |
| Genevestigator | Q62871 | |
| GO | GO:0005868 GO:0005874 GO:0031982 GO:0003774 GO:0032403 GO:0007018 GO:0006810 | |
| Gene3D | 2.130.10.10 | |
| InterPro | IPR025956 IPR015943 IPR001680 IPR017986 | |
| Pfam | PF11540 PF00400 | |
| SMART | SM00320 | |
| SUPFAM | SSF50978 | |
| PROSITE | PS50082 PS50294 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0031982 |
vesicle |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1990090 |
cellular response to nerve growth factor stimulus |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0044877 |
protein-containing complex binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
RGD:1303182 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010977 |
negative regulation of neuron projection development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007420 |
brain development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0045504 |
dynein heavy chain binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000277823 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0045503 |
dynein light chain binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003654 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030286 |
dynein complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000277823 |
C |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0008574 |
ATP-dependent microtubule motor activity, plus-end-directed |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000277823 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007018 |
microtubule-based movement |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003654 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005868 |
cytoplasmic dynein complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003654 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005868 |
cytoplasmic dynein complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007018 |
microtubule-based movement |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007018 |
microtubule-based movement |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005874 |
microtubule |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003774 |
motor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030286 |
dynein complex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Salata, MW et al. (2001) Growth factor regulation of cytoplasmic dynein intermediate chain subunit expression preceding neurite extension. J. Neurosci. Res. 65 408-16 PubMed GONUTS page
- ↑ 2.0 2.1 Vaughan, KT & Vallee, RB (1995) Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued. J. Cell Biol. 131 1507-16 PubMed GONUTS page
- ↑ 3.0 3.1 Hirayama, M et al. (2013) Integrated proteomics identified novel activation of dynein IC2-GR-COX-1 signaling in neurofibromatosis type I (NF1) disease model cells. Mol. Cell Proteomics 12 1377-94 PubMed GONUTS page
- ↑ Pfister, KK et al. (1996) Identification and developmental regulation of a neuron-specific subunit of cytoplasmic dynein. Mol. Biol. Cell 7 331-43 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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