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RAT:D3ZRK7

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) No Information Provided. (synonyms: Cdc6_predicted (ECO:0000313 with EMBL:EDM05961.1))
Protein Name(s) Cell division cycle 6 homolog (S. cerevisiae) (Predicted), isoform CRA_a (ECO:0000313 with EMBL:EDM05961.1)

Protein Cdc6 (ECO:0000313 with Ensembl:ENSRNOP00000032177)

External Links
UniProt D3ZRK7
EMBL AABR06065511
CH473948
CH473948
RefSeq NP_001101768.1
XP_006247416.1
UniGene Rn.219688
Ensembl ENSRNOT00000038228
GeneID 360621
KEGG rno:360621
CTD 990
RGD 1309157
GeneTree ENSGT00530000063498
KO K02213
OMA TPHLPPC
OrthoDB EOG7QG44J
PhylomeDB D3ZRK7
TreeFam TF101051
Reactome REACT_196414
REACT_199174
REACT_204904
REACT_206997
REACT_208829
REACT_209879
REACT_211117
REACT_212486
REACT_212543
REACT_213976
REACT_223712
REACT_249225
NextBio 673491
PRO PR:D3ZRK7
Proteomes UP000002494
GO GO:0005794
GO:0005634
GO:0051233
GO:0000922
GO:0005524
GO:0003682
GO:0051301
GO:0051984
GO:0032467
GO:0030071
Gene3D 1.10.10.10
3.40.50.300
InterPro IPR003593
IPR015163
IPR016314
IPR027417
IPR011991
Pfam PF09079
PIRSF PIRSF001767
SMART SM00382
SM01074
SUPFAM SSF52540

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1904385

cellular response to angiotensin

PMID:12063292[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1904117

cellular response to vasopressin

PMID:12063292[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048146

positive regulation of fibroblast proliferation

PMID:22223646[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0045737

positive regulation of cyclin-dependent protein serine/threonine kinase activity

PMID:22223646[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005575

cellular_component

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0033314

mitotic DNA replication checkpoint

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000080055
PomBase:SPBC14C8.07c
PomBase:SPBC29A10.15

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0035918
PANTHER:PTN000080129
PomBase:SPBC14C8.07c
UniProtKB:Q99741
WB:WBGene00000382

C

Seeded From UniProt

complete

enables

GO:0003688

DNA replication origin binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000080055
PomBase:SPBC29A10.15
SGD:S000003730
SGD:S000004530
UniProtKB:Q8I615

F

Seeded From UniProt

complete

involved_in

GO:0000278

mitotic cell cycle

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000080055
UniProtKB:Q99741

P

Seeded From UniProt

complete

involved_in

GO:0051984

positive regulation of chromosome segregation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99741
ensembl:ENSP00000209728

P

Seeded From UniProt

complete

part_of

GO:0051233

spindle midzone

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99741
ensembl:ENSP00000209728

C

Seeded From UniProt

complete

involved_in

GO:0032467

positive regulation of cytokinesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99741
ensembl:ENSP00000209728

P

Seeded From UniProt

complete

involved_in

GO:0030071

regulation of mitotic metaphase/anaphase transition

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99741
ensembl:ENSP00000209728

P

Seeded From UniProt

complete

enables

GO:0019900

kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99741
ensembl:ENSP00000209728

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99741
ensembl:ENSP00000209728

C

Seeded From UniProt

complete

part_of

GO:0000922

spindle pole

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99741
ensembl:ENSP00000209728

C

Seeded From UniProt

complete

involved_in

GO:0000278

mitotic cell cycle

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q99741
ensembl:ENSP00000209728

P

Seeded From UniProt

complete

involved_in

GO:0006270

DNA replication initiation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016314

P

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016314

P

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0132

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

involved_in

GO:0006270

DNA replication initiation

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000397764

P

Seeded From UniProt

complete

involved_in

GO:0051301

cell division

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000397764

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Fujita, N et al. (2002) Differences in E2F subunit expression in quiescent and proliferating vascular smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 283 H204-12 PubMed GONUTS page
  2. 2.0 2.1 Uranbileg, B et al. (2012) Cdc6 protein activates p27KIP1-bound Cdk2 protein only after the bound p27 protein undergoes C-terminal phosphorylation. J. Biol. Chem. 287 6275-83 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page