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RAT:ARK73
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Akr7a3 (synonyms: Afar, Akr7a1) | |
| Protein Name(s) | Aflatoxin B1 aldehyde reductase member 3
AFB1-AR Aflatoxin B1 aldehyde reductase member 1 rAFAR1 | |
| External Links | ||
| UniProt | P38918 | |
| EMBL | X74673 AF045464 AY230497 AY230491 AY230492 AY230493 AY230494 AY230495 AY230496 BC078872 BC089811 | |
| PIR | A48804 | |
| RefSeq | NP_037347.1 | |
| UniGene | Rn.6043 | |
| PDB | 1GVE | |
| PDBsum | 1GVE | |
| ProteinModelPortal | P38918 | |
| SMR | P38918 | |
| MINT | MINT-4564936 | |
| ChEMBL | CHEMBL2697 | |
| PhosphoSite | P38918 | |
| PaxDb | P38918 | |
| PRIDE | P38918 | |
| Ensembl | ENSRNOT00000024160 | |
| GeneID | 26760 | |
| KEGG | rno:26760 | |
| UCSC | RGD:628635 | |
| CTD | 22977 | |
| RGD | 628635 | |
| eggNOG | COG0667 | |
| GeneTree | ENSGT00550000074567 | |
| HOGENOM | HOG000250286 | |
| HOVERGEN | HBG050576 | |
| InParanoid | P38918 | |
| KO | K15303 | |
| OMA | GWEVAKP | |
| OrthoDB | EOG77127F | |
| PhylomeDB | P38918 | |
| TreeFam | TF329173 | |
| Reactome | REACT_261168 | |
| SABIO-RK | P38918 | |
| EvolutionaryTrace | P38918 | |
| NextBio | 608018 | |
| PRO | PR:P38918 | |
| Proteomes | UP000002494 | |
| Genevestigator | P38918 | |
| GO | GO:0005737 GO:0004032 GO:0004033 GO:0046223 GO:0046222 GO:0009636 | |
| Gene3D | 3.20.20.100 | |
| InterPro | IPR001395 IPR020471 IPR023210 | |
| PANTHER | PTHR11732 | |
| Pfam | PF00248 | |
| PRINTS | PR00069 | |
| SUPFAM | SSF51430 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0046223 |
aflatoxin catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046222 |
aflatoxin metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004033 |
aldo-keto reductase (NADP) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O95154 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O95154 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009636 |
response to toxic substance |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ellis, EM et al. (2003) Characterization of the rat aflatoxin B1 aldehyde reductase gene, AKR7A1. Structure and chromosomal localization of AKR7A1 as well as identification of antioxidant response elements in the gene promoter. Carcinogenesis 24 727-37 PubMed GONUTS page
- ↑ 2.0 2.1 Ellis, EM et al. (1993) An ethoxyquin-inducible aldehyde reductase from rat liver that metabolizes aflatoxin B1 defines a subfamily of aldo-keto reductases. Proc. Natl. Acad. Sci. U.S.A. 90 10350-4 PubMed GONUTS page
