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RABIT:GHR
Contents
| Species (Taxon ID) | Oryctolagus cuniculus (Rabbit). (9986) | |
| Gene Name(s) | GHR | |
| Protein Name(s) | Growth hormone receptor
GH receptor Somatotropin receptor Growth hormone-binding protein GH-binding protein GHBP Serum-binding protein | |
| External Links | ||
| UniProt | P19941 | |
| EMBL | AF015252 | |
| PIR | S08544 | |
| RefSeq | NP_001076105.1 | |
| UniGene | Ocu.2168 | |
| ProteinModelPortal | P19941 | |
| SMR | P19941 | |
| BioGrid | 1172345 | |
| DIP | DIP-313N | |
| IntAct | P19941 | |
| MINT | MINT-1535520 | |
| STRING | 9986.ENSOCUP00000007343 | |
| GeneID | 100009325 | |
| KEGG | ocu:100009325 | |
| CTD | 2690 | |
| eggNOG | ENOG410IFQI ENOG410XTHJ | |
| HOGENOM | HOG000015773 | |
| HOVERGEN | HBG005836 | |
| InParanoid | P19941 | |
| KO | K05080 | |
| PMAP-CutDB | P19941 | |
| Proteomes | UP000001811 | |
| GO | GO:0031904 GO:0005615 GO:0016021 GO:0005886 GO:0004896 GO:0017046 GO:0070064 GO:0006897 GO:0060396 GO:0042517 GO:0042523 | |
| Gene3D | 2.60.40.10 | |
| InterPro | IPR003961 IPR025871 IPR015152 IPR013783 IPR003528 | |
| Pfam | PF09067 PF00041 PF12772 | |
| SMART | SM00060 | |
| SUPFAM | SSF49265 | |
| PROSITE | PS50853 PS01352 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0019838 |
growth factor binding |
ECO:0000315 |
F |
seeded from uniprot |
complete | |||||
|
enables |
GO:0070064 |
proline-rich region binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060396 |
growth hormone receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042531 |
positive regulation of tyrosine phosphorylation of STAT protein |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0017046 |
peptide hormone binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019221 |
cytokine-mediated signaling pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004896 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004896 |
cytokine receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031904 |
endosome lumen |
Reactome:R-OCU-1169264 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-OCU-1169264 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006897 |
endocytosis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ DeSantis-Rodrigues, A et al. (2016) ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure. Invest. Ophthalmol. Vis. Sci. 57 1687-1698 PubMed GONUTS page
- ↑ Loesch, K et al. (2007) Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells. Endocrinology 148 5955-65 PubMed GONUTS page
- ↑ 3.0 3.1 Yi, W et al. (1996) Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase. Mol. Endocrinol. 10 1425-43 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Leung, DW et al. () Growth hormone receptor and serum binding protein: purification, cloning and expression. Nature 330 537-43 PubMed GONUTS page
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