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PSEAE:FMPO

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Species (Taxon ID) Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964)
Gene Name(s) pilA (synonyms: fimA)
Protein Name(s) Fimbrial protein

Pilin Strain PAO

External Links
UniProt P04739
EMBL M11323
AE004091
PIR A25023
RefSeq NP_253215.1
WP_003112842.1
PDB 1PAN
1PAO
PDBsum 1PAN
1PAO
ProteinModelPortal P04739
SMR P04739
STRING 208964.PA4525
TCDB 3.A.15.2.1
PRIDE P04739
DNASU 878423
EnsemblBacteria AAG07913
GeneID 878423
KEGG pae:PA4525
PATRIC 19843781
PseudoCAP PA4525
eggNOG COG4969
HOGENOM HOG000008197
KO K02650
OMA NSEDAGF
OrthoDB EOG6NWBPW
EvolutionaryTrace P04739
Proteomes UP000002438
GO GO:0044096
GO:0050848
GO:0016337
GO:0043107
InterPro IPR012902
IPR001082
Pfam PF13544
PF00114
TIGRFAMs TIGR02532
PROSITE PS00409

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005829

cytosol

PMID:25049409[1]

ECO:0000314

C

Figure 4b

complete
CACAO 10228

GO:0009986

cell surface

PMID:25049409[1]

ECO:0000314

C

Fig 4b

complete
CACAO 10260

part_of

GO:0009986

cell surface

PMID:25049409[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:25049409[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0098609

cell-cell adhesion

PMID:2897336[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050848

regulation of calcium-mediated signaling

PMID:23266901[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0044096

type IV pilus

PMID:2985436[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0044011

single-species biofilm formation on inanimate substrate

PMID:14507363[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043709

cell adhesion involved in single-species biofilm formation

PMID:16849183[6]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043107

type IV pilus-dependent motility

PMID:9224878[7]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043107

type IV pilus-dependent motility

PMID:12933890[8]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

PMID:10377148[9]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009289

pilus

PMID:2985436[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001082

P

Seeded From UniProt

complete

part_of

GO:0009289

pilus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001082

C

Seeded From UniProt

complete

part_of

GO:0009289

pilus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0281
UniProtKB-SubCell:SL-0113

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Chung, IY et al. (2014) A phage protein that inhibits the bacterial ATPase required for type IV pilus assembly. Proc. Natl. Acad. Sci. U.S.A. 111 11503-8 PubMed GONUTS page
  2. Doig, P et al. (1988) Role of pili in adhesion of Pseudomonas aeruginosa to human respiratory epithelial cells. Infect. Immun. 56 1641-6 PubMed GONUTS page
  3. Okuda, J et al. (2013) Type IV pilus protein PilA of Pseudomonas aeruginosa modulates calcium signaling through binding the calcium-modulating cyclophilin ligand. J. Infect. Chemother. 19 653-64 PubMed GONUTS page
  4. 4.0 4.1 Pasloske, BL et al. (1985) Cloning and sequencing of the Pseudomonas aeruginosa PAK pilin gene. FEBS Lett. 183 408-12 PubMed GONUTS page
  5. Klausen, M et al. (2003) Involvement of bacterial migration in the development of complex multicellular structures in Pseudomonas aeruginosa biofilms. Mol. Microbiol. 50 61-8 PubMed GONUTS page
  6. Jenkins, AT et al. (2005) Surface plasmon resonance shows that type IV pili are important in surface attachment by Pseudomonas aeruginosa. J R Soc Interface 2 255-9 PubMed GONUTS page
  7. Alm, RA & Mattick, JS (1997) Genes involved in the biogenesis and function of type-4 fimbriae in Pseudomonas aeruginosa. Gene 192 89-98 PubMed GONUTS page
  8. Zolfaghar, I et al. (2003) Twitching motility contributes to the role of pili in corneal infection caused by Pseudomonas aeruginosa. Infect. Immun. 71 5389-93 PubMed GONUTS page
  9. Comolli, JC et al. (1999) Pseudomonas aeruginosa gene products PilT and PilU are required for cytotoxicity in vitro and virulence in a mouse model of acute pneumonia. Infect. Immun. 67 3625-30 PubMed GONUTS page