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PMID:4366476

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Citation

Brenner, S (1974) The genetics of Caenorhabditis elegans. Genetics 77:71-94

Abstract

Methods are described for the isolation, complementation and mapping of mutants of Caenorhabditis elegans, a small free-living nematode worm. About 300 EMS-induced mutants affecting behavior and morphology have been characterized and about one hundred genes have been defined. Mutations in 77 of these alter the movement of the animal. Estimates of the induced mutation frequency of both the visible mutants and X chromosome lethals suggests that, just as in Drosophila, the genetic units in C. elegans are large.

Links

PubMed PMC1213120

Keywords

Animals; Chromosome Mapping; Crosses, Genetic; Female; Genes, Lethal; Genetic Complementation Test; Genetic Linkage; Genetics, Behavioral; Male; Mesylates/pharmacology; Movement; Mutation; Nematoda/drug effects; Nematoda/physiology; Nervous System Physiological Phenomena; Phenotype; Recombination, Genetic; Reproduction; Sex Chromosomes

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

CAEEL:C8JQR2

involved_in

GO:0043057: backward locomotion

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:G3MU01

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:G4SNP7

involved_in

GO:0010171: body morphogenesis

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00142900

P

Seeded From UniProt

complete

CAEEL:G4SNP7

involved_in

GO:0040018: positive regulation of multicellular organism growth

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00142900

P

Seeded From UniProt

complete

CAEEL:G5EBQ0

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00143164

P

Seeded From UniProt

complete

CAEEL:G5EBX1

involved_in

GO:0043057: backward locomotion

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:G5ECD3

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00143164

P

Seeded From UniProt

complete

CAEEL:G5EDM9

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00143164

P

Seeded From UniProt

complete

CAEEL:G5EE10

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00143164

P

Seeded From UniProt

complete

CAEEL:G5EEU6

involved_in

GO:0043057: backward locomotion

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:G5EEY3

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00143164

P

Seeded From UniProt

complete

CAEEL:G5EFN4

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00143164

P

Seeded From UniProt

complete

CAEEL:H9G2V2

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:H9G2V3

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:HM35

involved_in

GO:0040011: locomotion

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00143068

P

Seeded From UniProt

complete

CAEEL:JIP

involved_in

GO:0040011: locomotion

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:ACH2

involved_in

GO:0040011: locomotion

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:Q0PDK2

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00143164

P

Seeded From UniProt

complete

CAEEL:RIM

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:ACH5

involved_in

GO:0040011: locomotion

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:CAPS

involved_in

GO:0007626: locomotory behavior

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:UNC53

involved_in

GO:0043057: backward locomotion

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:Q9TXR6

involved_in

GO:0010171: body morphogenesis

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00142900

P

Seeded From UniProt

complete

CAEEL:Q9TXR6

involved_in

GO:0040018: positive regulation of multicellular organism growth

ECO:0000315: mutant phenotype evidence used in manual assertion

WB:WBVar00142900

P

Seeded From UniProt

complete

See also

References

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