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PMID:27066371
| Citation |
Zhang, CC, Gu, WL, Wu, XM, Li, YM, Chen, CX and Huang, XY Active components from Radix Scrophulariae inhibits the ventricular remodeling induced by hypertension in rats. Springerplus 5:358 |
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| Abstract |
In the previous study, active extract of Radix Scrophularia (ACRS) demonstrated beneficial effects on ventricular remodeling induced by coronary artery ligation and lowered blood pressure in rats. And ACRS also exhibited the effect on lowering the blood pressure in spontaneously hypertensive rats (SHRs). The aim of this study is to explore the effects of ACRS on ventricular remodeling in SHRs and underlying mechanisms. |
| Links |
PubMed Online version:10.1186/s40064-016-1985-z |
| Keywords |
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Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0070372: regulation of ERK1 and ERK2 cascade |
ECO:0000314: |
P |
Fig.4 shows the effects of active components of Radix Scrophulariae (ACRS) on phospho-specific extracellular signal regulated kinase (ERK 1/2). |
complete | ||||
Notes
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References
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