GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

PMID:2513223

From GONUTS
Jump to: navigation, search
Citation

Ahmed, F, Lundin, LG and Shire, JG (1989) Lysosomal mutations increase susceptibility to anaesthetics. Experientia 45:1133-5

Abstract

The anaesthetic responses of homozygous mutant mice were compared with those of their normal heterozygous littermates. The two recessive mutations studied were beige (bg) and reduced pigmentation (rp). Homozygosity for either significantly increased the sleeping time of both sexes after treatment with pentobarbital, tribromoethanol or the steroid anaesthetic alphaxalone.

Links

PubMed

Keywords

Anesthesia; Anesthetics; Animals; Ethanol; Female; Homozygote; Lysosomes/physiology; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mutation; Pentobarbital; Pigmentation/genetics; Pregnanediones; Time Factors

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

See Help:References for how to manage references in GONUTS.