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PMID:2423416

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Citation

Nishide, T, Nakamura, Y, Emi, M, Yamamoto, T, Ogawa, M, Mori, T and Matsubara, K (1986) Primary structure of human salivary alpha-amylase gene. Gene 41:299-304

Abstract

A recombinant clone which covers the human salivary alpha-amylase gene in a single insert has been isolated from a human genomic DNA library using a human salivary alpha-amylase cDNA as a probe. Restriction mapping and nucleotide (nt) sequence analysis revealed that this gene is approx. 10 kb long and is separated into eleven exons by ten introns. Its 5'-flanking region has some sequence homology with that of mouse salivary alpha-amylase gene [Schibler et al., J. Mol. Biol. 155 (1982) 247-266].

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PubMed

Keywords

Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA/analysis; DNA Restriction Enzymes; Genes; Humans; Liver/enzymology; Mice; Microscopy, Electron; Molecular Weight; Pancreas/enzymology; Poly A/genetics; RNA/genetics; RNA, Messenger; Saliva/enzymology; Transcription, Genetic; alpha-Amylases/genetics

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status


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References

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