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PMID:22727700

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Citation

Zhang, Y, Wang, H, Kage-Nakadai, E, Mitani, S and Wang, X (2012) C. elegans secreted lipid-binding protein NRF-5 mediates PS appearance on phagocytes for cell corpse engulfment. Curr. Biol. 22:1276-84

Abstract

During programmed cell death, apoptotic cells are rapidly removed by phagocytes. How dying cells are recognized remains poorly understood.

Links

PubMed Online version:10.1016/j.cub.2012.06.004

Keywords


Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

CAEEL:TTR52

enables

GO:0005515: protein binding

ECO:0000353: physical interaction evidence used in manual assertion

WB:WBGene00003812

F

Seeded From UniProt

complete

CAEEL:NRF5

enables

GO:0005515: protein binding

ECO:0000353: physical interaction evidence used in manual assertion

WB:WBGene00008719

F

Seeded From UniProt

complete

CAEEL:NRF5

located_in

GO:0005576: extracellular region

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

CAEEL:NRF5

involved_in

GO:0006869: lipid transport

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

CAEEL:NRF5

enables

GO:0001786: phosphatidylserine binding

ECO:0000314: direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

CAEEL:NRF5

involved_in

GO:1901076: positive regulation of engulfment of apoptotic cell

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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