GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

PMID:22307646

From GONUTS
Jump to: navigation, search
Citation

Uemura, T, Kim, H, Saito, C, Ebine, K, Ueda, T, Schulze-Lefert, P and Nakano, A (2012) Qa-SNAREs localized to the trans-Golgi network regulate multiple transport pathways and extracellular disease resistance in plants. Proc. Natl. Acad. Sci. U.S.A. 109:1784-9

Abstract

In all eukaryotic cells, a membrane-trafficking system connects the post-Golgi organelles, such as the trans-Golgi network (TGN), endosomes, vacuoles, and the plasma membrane. This complex network plays critical roles in several higher-order functions in multicellular organisms. The TGN, one of the important organelles for protein transport in the post-Golgi network, functions as a sorting station, where cargo proteins are directed to the appropriate post-Golgi compartments. Unlike its roles in animal and yeast cells, the TGN has also been reported to function like early endosomal compartments in plant cells. However, the physiological roles of the TGN functions in plants are not understood. Here, we report a study of the SYP4 group (SYP41, SYP42, and SYP43), which represents the plant orthologs of the Tlg2/syntaxin16 Qa-SNARE (soluble N-ethylmaleimide sensitive factor attachment protein receptor) that localizes on the TGN in yeast and animal cells. The SYP4 group regulates the secretory and vacuolar transport pathways in the post-Golgi network and maintains the morphology of the Golgi apparatus and TGN. Consistent with a secretory role, SYP4 proteins are required for extracellular resistance responses to a fungal pathogen. We also reveal a plant cell-specific higher-order role of the SYP4 group in the protection of chloroplasts from salicylic acid-dependent biotic stress.

Links

PubMed PMC3277133 Online version:10.1073/pnas.1115146109

Keywords

Arabidopsis/metabolism; Biological Transport; Cell Compartmentation; Golgi Apparatus/metabolism; Plant Diseases; SNARE Proteins/metabolism

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

ARATH:SYP41

located_in

GO:0005802: trans-Golgi network

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

ARATH:SYP43

located_in

GO:0005802: trans-Golgi network

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

ARATH:SYP43

acts_upstream_of_or_within

GO:0007034: vacuolar transport

ECO:0000316: genetic interaction evidence used in manual assertion

AGI_LocusCode:AT4G02195

P

Seeded From UniProt

complete

ARATH:SYP43

acts_upstream_of_or_within

GO:0007030: Golgi organization

ECO:0000316: genetic interaction evidence used in manual assertion

AGI_LocusCode:AT4G02195

P

Seeded From UniProt

complete

ARATH:SYP43

acts_upstream_of_or_within

GO:0009306: protein secretion

ECO:0000316: genetic interaction evidence used in manual assertion

AGI_LocusCode:AT4G02195

P

Seeded From UniProt

complete

ARATH:SYP42

located_in

GO:0005802: trans-Golgi network

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

ARATH:SYP42

acts_upstream_of_or_within

GO:0007034: vacuolar transport

ECO:0000316: genetic interaction evidence used in manual assertion

AGI_LocusCode:AT4G02195

P

Seeded From UniProt

complete

ARATH:SYP42

acts_upstream_of_or_within

GO:0007030: Golgi organization

ECO:0000316: genetic interaction evidence used in manual assertion

AGI_LocusCode:AT3G05710

P

Seeded From UniProt

complete

ARATH:SYP42

acts_upstream_of_or_within

GO:0009306: protein secretion

ECO:0000316: genetic interaction evidence used in manual assertion

AGI_LocusCode:AT3G05710

P

Seeded From UniProt

complete

ARATH:SYP42

acts_upstream_of_or_within

GO:1900150: regulation of defense response to fungus

ECO:0000316: genetic interaction evidence used in manual assertion

AGI_LocusCode:AT3G05710

P

Seeded From UniProt

complete


See also

References

See Help:References for how to manage references in GONUTS.