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PMID:20546121

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Citation

Cosemans, JM, Van Kruchten, R, Olieslagers, S, Schurgers, LJ, Verheyen, FK, Munnix, IC, Waltenberger, J, Angelillo-Scherrer, A, Hoylaerts, MF, Carmeliet, P and Heemskerk, JW (2010) Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization. J. Thromb. Haemost. 8:1797-808

Abstract

 Interaction of murine Gas6 with the platelet Gas6 receptors Tyro3, Axl and Mer (TAM) plays an important role in arterial thrombus formation. However, a role for Gas6 in human platelet activation has been questioned.

Links

PubMed Online version:10.1111/j.1538-7836.2010.03935.x

Keywords

Animals; Humans; Intercellular Signaling Peptides and Proteins/metabolism; Mice; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism; Proto-Oncogene Proteins/metabolism; Receptor Protein-Tyrosine Kinases/metabolism; Recombinant Proteins/chemistry; Signal Transduction; Thrombosis/metabolism; Thrombosis/pathology

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

MOUSE:TYRO3

involved_in

GO:0070527: platelet aggregation

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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