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PMID:20298225

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Citation

Fulton, L, Vaddepalli, P, Yadav, RK, Batoux, M and Schneitz, K (2010) Inter-cell-layer signalling during Arabidopsis ovule development mediated by the receptor-like kinase STRUBBELIG. Biochem. Soc. Trans. 38:583-7

Abstract

Plant organs, such as ovules and flowers, arise through cellular events that are precisely co-ordinated between cells within and across clonally distinct cell layers. Receptor-like kinases are cell-surface receptors that perceive and relay intercellular information. In Arabidopsis the leucine-rich repeat receptor-like kinase STRUBBELIG (SUB) is required for integument initiation and outgrowth during ovule development, floral organ shape and the control of the cell division plane in the first subepidermal cell layer of floral meristems, among other functions. A major goal is to understand SUB-mediated signal transduction at the molecular level. Present evidence suggests that SUB affects neighbouring cells in a non-cell-autonomous fashion. In addition, our results indicate that SUB is an atypical, or kinase-dead, kinase. Forward genetics identified three genes, QUIRKY (QKY), ZERZAUST and DETORQUEO, that are thought to contribute to SUB-dependent signal transduction. QKY encodes a predicted membrane-bound protein with four cytoplasmic C(2) domains. By analogy to animal proteins with related domain topology, we speculate that QKY may be involved in Ca(2+)-dependent signalling and membrane trafficking. Studying SUB-dependent signalling will contribute to our understanding of how atypical kinases mediate signal transduction and how cells co-ordinate their behaviour to allow organs, such as ovules, to develop their three-dimensional architecture.

Links

PubMed Online version:10.1042/BST0380583

Keywords

Arabidopsis/embryology; Arabidopsis/growth & development; Arabidopsis/physiology; Arabidopsis Proteins/genetics; Arabidopsis Proteins/physiology; Body Patterning/genetics; Cell Communication/genetics; Cell Communication/physiology; Gene Expression Regulation, Plant; Models, Biological; Ovule/embryology; Ovule/growth & development; Ovule/physiology; Protein Kinases/genetics; Protein Kinases/physiology; Signal Transduction/physiology

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

ARATH:SUB

acts_upstream_of_or_within

GO:0000902: cell morphogenesis

ECO:0000270: expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:SUB

acts_upstream_of_or_within

GO:0000902: cell morphogenesis

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:SUB

located_in

GO:0005886: plasma membrane

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

ARATH:SUB

acts_upstream_of_or_within

GO:0010071: root meristem specification

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:SUB

acts_upstream_of_or_within

GO:0048437: floral organ development

ECO:0000270: expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:SUB

acts_upstream_of_or_within

GO:0048367: shoot system development

ECO:0000304: author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete


See also

References

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