GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:19945098
| Citation |
Lee, CL, Chiu, PC, Lam, KK, Chan, RW, Chu, IK, Koistinen, R, Koistinen, H, Seppälä, M, Lee, KF and Yeung, WS (2010) Glycodelin-A modulates cytokine production of peripheral blood natural killer cells. Fertil. Steril. 94:769-71 |
|---|---|
| Abstract |
Glycodelin-A increased the secretion of interleukin-6, interleukin-13, and granulocyte-macrophage colony-stimulating factor from natural killer cells in the peripheral blood but does not affect their viability, cell death, and cytotoxicity. These data suggest that glycodelin-A contributes to the cytokine shift in early pregnancy. |
| Links |
PubMed Online version:10.1016/j.fertnstert.2009.10.009 |
| Keywords |
Cell Death/immunology; Cell Survival/immunology; Cytokines/immunology; Cytokines/metabolism; Decidua/cytology; Decidua/immunology; Decidua/metabolism; Female; Glycoproteins/immunology; Glycoproteins/metabolism; Glycoproteins/pharmacology; Granulocyte-Macrophage Colony-Stimulating Factor/immunology; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism; Humans; Interleukin-13/immunology; Interleukin-13/metabolism; Interleukin-6/immunology; Interleukin-6/metabolism; Killer Cells, Natural/cytology; Killer Cells, Natural/drug effects; Killer Cells, Natural/immunology; Pregnancy; Pregnancy Proteins/immunology; Pregnancy Proteins/metabolism; Pregnancy Proteins/pharmacology; Pregnancy Trimester, First/immunology; Pregnancy Trimester, First/metabolism; Trophoblasts/cytology; Trophoblasts/immunology; Trophoblasts/metabolism |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:2000778: positive regulation of interleukin-6 secretion |
ECO:0000314: |
P |
Table 1 |
complete | ||||
| GO:2000667: positive regulation of interleukin-13 secretion |
ECO:0000314: |
P |
Table 1 |
complete | ||||
| GO:0032725: positive regulation of granulocyte macrophage colony-stimulating factor production |
ECO:0000314: |
P |
Table 1 |
complete | ||||
|
involved_in |
GO:2000778: positive regulation of interleukin-6 secretion |
ECO:0000314: direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:2000667: positive regulation of interleukin-13 secretion |
ECO:0000314: direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032725: positive regulation of granulocyte macrophage colony-stimulating factor production |
ECO:0000314: direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
See also
References
See Help:References for how to manage references in GONUTS.
