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PMID:19606897
| Citation |
Jian, X, Wasinger, EC, Lockard, JV, Chen, LX and He, C (2009) Highly sensitive and selective gold(I) recognition by a metalloregulator in Ralstonia metallidurans. J. Am. Chem. Soc. 131:10869-71 |
|---|---|
| Abstract |
A MerR family metalloregulatory protein CupR selectively responds to gold stress in Ralstonia metallidurans. A distorted trigonal geometry appears to be used by CupR to achieve the highly sensitive (K(d) approximately 10(-35) M) and selective recognition of gold(I). |
| Links |
PubMed Online version:10.1021/ja904279n |
| Keywords |
Bacterial Proteins/metabolism; Gold/pharmacokinetics; Protein Binding; Ralstonia/metabolism |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0071248: cellular response to metal ion |
ECO:0000270: |
P |
Figure 2: Northern Blot analysis shows induction of cupR in the presence of gold ions. Expression is increased with increased gold concentration. No GO term for "response to gold ion" available. |
complete | ||||
See also
References
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