GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

PMID:19572019

From GONUTS
Jump to: navigation, search
Citation

Kategaya, LS, Changkakoty, B, Biechele, T, Conrad, WH, Kaykas, A, Dasgupta, R and Moon, RT (2009) Bili inhibits Wnt/beta-catenin signaling by regulating the recruitment of axin to LRP6. PLoS ONE 4:e6129

Abstract

Insights into how the Frizzled/LRP6 receptor complex receives, transduces and terminates Wnt signals will enhance our understanding of the control of the Wnt/ss-catenin pathway.

Links

PubMed PMC2701632 Online version:10.1371/journal.pone.0006129

Keywords

Animals; Axin Protein; Base Sequence; Cells, Cultured; Cytoskeletal Proteins/metabolism; DNA Primers; Humans; Immunoprecipitation; In Situ Hybridization; Low Density Lipoprotein Receptor-Related Protein-6; Membrane Proteins/metabolism; Protein Binding; RNA Interference; Receptors, LDL/metabolism; Repressor Proteins/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Wnt Proteins/metabolism; beta Catenin/metabolism

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

DANRE:FRMD8

involved_in

GO:0030178: negative regulation of Wnt signaling pathway

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-4

P

Seeded From UniProt

complete

DANRE:FRMD8

involved_in

GO:0030178: negative regulation of Wnt signaling pathway

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-3

P

Seeded From UniProt

complete

DANRE:FRMD8

involved_in

GO:0009952: anterior/posterior pattern specification

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-4

P

Seeded From UniProt

complete

DANRE:FRMD8

involved_in

GO:0009952: anterior/posterior pattern specification

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-3

P

Seeded From UniProt

complete

DANRE:FRMD8

involved_in

GO:0060828: regulation of canonical Wnt signaling pathway

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-4

P

Seeded From UniProt

complete

DANRE:FRMD8

involved_in

GO:0060828: regulation of canonical Wnt signaling pathway

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-GENE-980526-332,ZFIN:ZDB-MRPHLNO-090812-3

P

Seeded From UniProt

complete

DROME:Q9VBX0

colocalizes_with

GO:0005886: plasma membrane

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

DROME:Q9VBX0

involved_in

GO:0090090: negative regulation of canonical Wnt signaling pathway

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

DANRE:WNT8A

involved_in

GO:0009952: anterior/posterior pattern specification

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

See Help:References for how to manage references in GONUTS.