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PMID:19392685

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Citation

Saedler, R, Jakoby, M, Marin, B, Galiana-Jaime, E and Hülskamp, M (2009) The cell morphogenesis gene SPIRRIG in Arabidopsis encodes a WD/BEACH domain protein. Plant J. 59:612-21

Abstract

WD40/BEACH domain proteins have been implicated in membrane trafficking and membrane composition events in Dictyostelium and Drosophila. In this paper, we show that the Arabidopsis SPIRRIG (SPI) gene encodes a WD40/BEACH domain protein. The cellular analysis revealed fragmented vacuoles in root hairs similar to those found in the corresponding Dictyostelium mutants, suggesting a related cellular function. The phenotypic analysis revealed that spi mutants share all phenotypic aspects of mutants in the actin polymerization-regulating ARP2/3 pathway, including distorted trichomes, less lobing of epidermal pavement cells, disconnected epidermal cells on various organs, and shorter root hairs. This complete phenotypic overlap suggests that this WD40/BEACH domain protein and the actin-regulating ARP2/3 pathway are involved in similar growth processes.

Links

PubMed Online version:10.1111/j.1365-313X.2009.03900.x

Keywords

Actin-Related Protein 2-3 Complex/metabolism; Arabidopsis/cytology; Arabidopsis/genetics; Arabidopsis/metabolism; Arabidopsis Proteins/genetics; Arabidopsis Proteins/metabolism; Chromosome Mapping; Cloning, Molecular; DNA, Plant/genetics; Gene Expression Regulation, Plant; Genes, Plant; Mutation; Phylogeny; Plant Roots/cytology; Plant Roots/genetics; Vacuoles/ultrastructure

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

ARATH:BCHA1

acts_upstream_of_or_within

GO:0007033: vacuole organization

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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