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PMID:19390821

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Citation

Lee, SJ, Cho, DI, Kang, JY and Kim, SY (2009) An ARIA-interacting AP2 domain protein is a novel component of ABA signaling. Mol. Cells 27:409-16

Abstract

ADAP is an AP2-domain protein that interacts with ARIA, which, in turn, interacts with ABF2, a bZIP class transcription factor. ABF2 regulates various aspects of the abscisic acid (ABA) response by controlling the expression of a subset of ABA-responsive genes. Our expression analyses indicate that ADAP is expressed in roots, emerging young leaves, and flowers. We found that adap knockout mutant lines germinate more efficiently than wild-type plants and that the mutant seedlings grow faster. This suggests that ADAP is involved in the regulation of germination and seedling growth. Both germination and post-germination growth of the knockout mutants were partially insensitive to ABA, which indicates that ADAP is required for a full ABA response. The survival rates for mutants from which water was withheld were low compared with those for wild-type plants. The result shows that ADAP is necessary for the response to stress induced by water deprivation. Together, our data indicate that ADAP is a positive regulator of the ABA response and is also involved in regulating seedling growth. The role of ADAP is similar to that of ARIA, which is also a positive regulator of the ABA response. It appears that ADAP acts through the same ABA response pathway as ARIA.

Links

PubMed Online version:10.1007/s10059-009-0058-3

Keywords

Abscisic Acid/genetics; Abscisic Acid/metabolism; Amino Acid Sequence; Arabidopsis/genetics; Arabidopsis/growth & development; Arabidopsis/metabolism; Arabidopsis Proteins/genetics; Arabidopsis Proteins/metabolism; DNA-Binding Proteins/genetics; DNA-Binding Proteins/metabolism; Droughts; Gene Expression Profiling; Gene Expression Regulation, Developmental; Germination/genetics; Germination/physiology; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Molecular Sequence Data; Plant Growth Regulators/genetics; Plant Growth Regulators/metabolism; Plants, Genetically Modified/genetics; Plants, Genetically Modified/metabolism; Seedling/genetics; Seedling/growth & development; Seedling/metabolism; Signal Transduction; Stress, Physiological; Transcription Factor AP-2/genetics; Transcription Factor AP-2/metabolism; Transcription Factors/genetics; Transcription Factors/metabolism; Two-Hybrid System Techniques

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

ARATH:AP2L1

acts_upstream_of_or_within

GO:0010187: negative regulation of seed germination

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:AP2L1

acts_upstream_of_or_within

GO:0009737: response to abscisic acid

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:AP2L1

acts_upstream_of_or_within

GO:0009651: response to salt stress

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:AP2L1

acts_upstream_of_or_within

GO:0009414: response to water deprivation

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:AP2L1

acts_upstream_of_or_within

GO:0040008: regulation of growth

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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