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PMID:18577655

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Citation

Browning, AC, Dua, HS and Amoaku, WM (2008) The effects of growth factors on the proliferation and in vitro angiogenesis of human macular inner choroidal endothelial cells. Br J Ophthalmol 92:1003-8

Abstract

To investigate the effect of VEGF(165), FGF2, IGF-1, PDGF-AA, PDGF-BB and IL-1 beta on the proliferation and angiogenic tube formation of human macular inner choroidal endothelial cells (ICEC).

Links

PubMed Online version:10.1136/bjo.2007.127670

Keywords

Cell Count; Cell Proliferation/drug effects; Cells, Cultured; Choroid/cytology; Choroid/drug effects; Choroidal Neovascularization/pathology; Dose-Response Relationship, Drug; Endothelial Cells/drug effects; Fibroblast Growth Factor 2/pharmacology; Growth Substances/pharmacology; Humans; Vascular Endothelial Growth Factor A/pharmacology

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

HUMAN:VEGFA

involved_in

GO:0045766: positive regulation of angiogenesis

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

HUMAN:VEGFA

involved_in

GO:0001938: positive regulation of endothelial cell proliferation

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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