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PMID:18540080

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Citation

Nakayama, K, Okawa, K, Kakizaki, T and Inaba, T (2008) Evaluation of the protective activities of a late embryogenesis abundant (LEA) related protein, Cor15am, during various stresses in vitro. Biosci. Biotechnol. Biochem. 72:1642-5

Abstract

Arabidopsis Cor15am is a late embryogenesis abundant (LEA) related protein that has been shown to exhibit cryoprotective activity in vitro. In this study, we further investigated the mechanisms by which Cor15am protects substrates from inactivation. Although Cor15am did not exhibit refolding activity, it showed protective activity against various stresses in vitro. This might be attributable to the activity of Cor15am in attenuating the aggregation of the substrates. Our data indicate that Cor15am functions as a protectant against various stresses by preventing protein aggregation.

Links

PubMed

Keywords

Arabidopsis/embryology; Arabidopsis/genetics; Arabidopsis/metabolism; Arabidopsis Proteins/genetics; Arabidopsis Proteins/metabolism; Genes, Reporter/genetics; L-Lactate Dehydrogenase/metabolism; Water/metabolism

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

ARATH:CR15A

involved_in

GO:0009631: cold acclimation

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:CR15A

involved_in

GO:0009819: drought recovery

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:CR15A

involved_in

GO:0010286: heat acclimation

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:CR15A

acts_upstream_of_or_within

GO:0050821: protein stabilization

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:CR15A

NOT|involved_in

GO:0061077: chaperone-mediated protein folding

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:Q42512

NOT|involved_in

GO:0061077: chaperone-mediated protein folding

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:Q42512

involved_in

GO:0050821: protein stabilization

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:Q42512

involved_in

GO:0010286: heat acclimation

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:Q42512

involved_in

GO:0009819: drought recovery

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

ARATH:Q42512

involved_in

GO:0009631: cold acclimation

ECO:0000314: direct assay evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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