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PMID:18178574

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Citation

Domínguez, JN, de la Rosa, A, Navarro, F, Franco, D and Aránega, AE (2008) Tissue distribution and subcellular localization of the cardiac sodium channel during mouse heart development. Cardiovasc. Res. 78:45-52

Abstract

The aim of this study was to analyse the mRNA expression levels and protein distribution of the cardiac sodium channel Scn5a/Nav1.5 during mouse cardiogenesis.

Links

PubMed Online version:10.1093/cvr/cvm118

Keywords

Animals; Cell Differentiation; Gene Expression Regulation, Developmental; Heart/embryology; Heart/growth & development; Immunohistochemistry; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Myocardium/cytology; Myocardium/metabolism; RNA, Messenger/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sodium Channels/genetics; Sodium Channels/metabolism; Tissue Distribution

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

MOUSE:CXA1

located_in

GO:0014704: intercalated disc

ECO:0000314: direct assay evidence used in manual assertion

C

  • part_of:(CL:0000746)
  • part_of:(EMAPA:32746)

Seeded From UniProt

complete

MOUSE:SCN1B

located_in

GO:0014704: intercalated disc

ECO:0000314: direct assay evidence used in manual assertion

C

  • part_of:(CL:0000746)
  • part_of:(EMAPA:32746)

Seeded From UniProt

complete

MOUSE:SCN1B

located_in

GO:0030315: T-tubule

ECO:0000314: direct assay evidence used in manual assertion

C

  • part_of:(CL:0000746)
  • part_of:(EMAPA:32746)

Seeded From UniProt

complete

MOUSE:SCN5A

located_in

GO:0014704: intercalated disc

ECO:0000314: direct assay evidence used in manual assertion

C

  • part_of:(CL:0000746)
  • part_of:(EMAPA:32746)

Seeded From UniProt

complete

MOUSE:SCN5A

located_in

GO:0030315: T-tubule

ECO:0000314: direct assay evidence used in manual assertion

C

  • part_of:(CL:0000746)
  • part_of:(EMAPA:32746)

Seeded From UniProt

complete

MOUSE:CXA1

part_of

GO:0014704: intercalated disc

ECO:0000314: direct assay evidence used in manual assertion

C

  • part_of:(EMAPA:32746)
  • part_of:(CL:0000746)

Seeded From UniProt

complete


See also

References

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