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PMID:18031608
| Citation |
Shi, YH, Zhao, S, Wang, C, Li, Y and Duan, HJ (2007) Fluvastatin inhibits activation of JAK and STAT proteins in diabetic rat glomeruli and mesangial cells under high glucose conditions. Acta Pharmacol. Sin. 28:1938-46 |
|---|---|
| Abstract |
The aim of the present study was to further elucidate the mechanism of the protective role of fluvastatin on diabetic nephropathy. |
| Links |
PubMed Online version:10.1111/j.1745-7254.2007.00653.x |
| Keywords |
Animals; Anticholesteremic Agents/pharmacology; Base Sequence; DNA Primers; Diabetic Retinopathy/enzymology; Diabetic Retinopathy/metabolism; Enzyme Activation; Fatty Acids, Monounsaturated/pharmacology; Glomerular Mesangium/drug effects; Glomerular Mesangium/enzymology; Glomerular Mesangium/metabolism; Indoles/pharmacology; Janus Kinases/antagonists & inhibitors; Janus Kinases/metabolism; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; STAT Transcription Factors/antagonists & inhibitors; STAT Transcription Factors/metabolism |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0014070: response to organic cyclic compound |
ECO:0000270: expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042493: response to drug |
ECO:0000270: expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
See also
References
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