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PMID:17690043

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Citation

Liu, T, Wang, CY, Gou, SM, Wu, HS, Xiong, JX and Zhou, J (2007) PDX-1 expression and proliferation of duct epithelial cells after partial pancreatectomy in rats. HBPD INT 6:424-9

Abstract

The pancreas has a strong regeneration potential in mammals. Previous studies suggested that pancreas regeneration is correlated with proliferation and differentiation of pancreatic stem cells, but the field of pancreatic stem cells is still in its infancy. This study was undertaken to detect the expression of pancreas/duodenal homeobox-1 (PDX-1) and proliferation of pancreatic duct epithelial cells in remnant pancreas during regeneration after partial pancreatectomy in rats, and characterize the source of pancreatic stem cells.

Links

PubMed

Keywords

Animals; Bromodeoxyuridine/pharmacology; Cell Proliferation; Epithelial Cells/metabolism; Homeodomain Proteins/biosynthesis; Immunohistochemistry; Islets of Langerhans Transplantation/methods; Pancreas/pathology; Pancreas/surgery; Pancreatectomy; Pancreatic Ducts/metabolism; Pancreatic Ducts/pathology; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells/cytology; Trans-Activators/biosynthesis

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

RAT:PDX1

involved_in

GO:0031100: animal organ regeneration

ECO:0000270: expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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