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PMID:17076625

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Citation

Kaneko, Y, Saito, M, Mori, A, Sakamoto, K, Nakahara, T and Ishii, K (2006) Vasodilator effects of adrenomedullin on retinal arterioles in streptozotocin-induced diabetic rats. J Ocul Pharmacol Ther 22:317-22

Abstract

The aim of this study was to examine whether diabetes changes the in vivo effects of adrenomedullin (ADM) on diameter of retinal arteriole and blood pressure in rats.

Links

PubMed Online version:10.1089/jop.2006.22.317

Keywords

Adrenomedullin/pharmacology; Animals; Blood Glucose/analysis; Blood Pressure/drug effects; Diabetes Mellitus, Experimental/chemically induced; Diabetes Mellitus, Experimental/physiopathology; Heart Rate/drug effects; Male; Rats; Rats, Wistar; Retinal Artery/anatomy & histology; Retinal Artery/drug effects; Retinal Artery/physiopathology; Streptozocin; Vasodilator Agents/pharmacology

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

RAT:ADML

involved_in

GO:0097755: positive regulation of blood vessel diameter

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

See Help:References for how to manage references in GONUTS.