PMID:16432587

Citation	Al-Ayadhi, LY, Korish, AA and Al-Tuwaijri, AS (2006) The effect of vitamin E, L-arginine, N-nitro L-arginine methyl ester and forskolin on endocrine and metabolic changes of rats exposed to acute cold stress. Saudi Med J 27:17-22
Abstract	It is a well documented fact that under stress conditions the hypothalamic-pituitary-adrenal axis (HPA) and the sympathetic nervous system (SNS) are stimulated. This results in a series of neural and endocrine adaptations known as the stress response. The current study assessed the effects of acute cold stress on adrenomedullin (ADM) levels in plasma and peripheral tissues (kidneys and heart) of rats, as well as on blood glucose, cholesterol, triglycerides (TG), total proteins both before and after intraperitoneal administration of each of the following: vitamin-E, L-arginine, forskolin and L-NAME.
Links	PubMed
Keywords	Adrenomedullin; Animals; Arginine/administration & dosage; Arginine/pharmacology; Blood Glucose/analysis; Cholesterol/blood; Cold Temperature; Forskolin/administration & dosage; Forskolin/pharmacology; Heart/drug effects; Injections, Intraperitoneal; Kidney/drug effects; Kidney/metabolism; Myocardium/metabolism; NG-Nitroarginine Methyl Ester/administration & dosage; NG-Nitroarginine Methyl Ester/pharmacology; Peptides/blood; Rats; Rats, Wistar; Stress, Physiological/blood; Stress, Physiological/etiology; Stress, Physiological/metabolism; Tissue Plasminogen Activator/metabolism; Vitamin E/administration & dosage; Vitamin E/pharmacology
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Annotations

Gene product	Qualifier	GO Term	Evidence Code	with/from	Aspect	Extension	Notes	Status
RAT:ADML	involved_in	GO:0009409: response to cold	ECO:0000270: expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete

References

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