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PMID:15797017

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Citation

Weidinger, G, Thorpe, CJ, Wuennenberg-Stapleton, K, Ngai, J and Moon, RT (2005) The Sp1-related transcription factors sp5 and sp5-like act downstream of Wnt/beta-catenin signaling in mesoderm and neuroectoderm patterning. Curr. Biol. 15:489-500

Abstract

Wnt/beta-catenin signaling regulates many processes during vertebrate development, including patterning of the mesoderm along the dorso-ventral axis and patterning of the neuroectoderm along the anterior-posterior axis during gastrulation. However, relatively little is known about Wnt target genes mediating these effects.

Links

PubMed Online version:10.1016/j.cub.2005.01.041

Keywords

Animals; Body Patterning/physiology; Cloning, Molecular; Cytoskeletal Proteins/metabolism; Ectoderm/physiology; Gene Expression Regulation, Developmental; Intercellular Signaling Peptides and Proteins/metabolism; Luciferases; Mesoderm/physiology; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Rhombencephalon/embryology; Signal Transduction/physiology; Trans-Activators/metabolism; Wnt Proteins; Zebrafish/embryology; Zebrafish Proteins/metabolism; beta Catenin

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

DANRE:B0S6I8

involved_in

GO:0048332: mesoderm morphogenesis

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050607-2,ZFIN:ZDB-MRPHLNO-050901-1

P

Seeded From UniProt

complete

DANRE:WNT8A

involved_in

GO:0030902: hindbrain development

ECO:0000315: mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13

P

Seeded From UniProt

complete

DANRE:WNT8A

involved_in

GO:0030902: hindbrain development

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-050607-2

P

Seeded From UniProt

complete

DANRE:Q1JPX0

involved_in

GO:0030902: hindbrain development

ECO:0000315: mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050607-2

P

Seeded From UniProt

complete

DANRE:Q1JPX0

involved_in

GO:0030902: hindbrain development

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-050607-2

P

Seeded From UniProt

complete

DANRE:Q1JPX0

involved_in

GO:0016055: Wnt signaling pathway

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-050607-2

P

Seeded From UniProt

complete

DANRE:Q1JPX0

involved_in

GO:0048332: mesoderm morphogenesis

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050607-2,ZFIN:ZDB-MRPHLNO-050901-1

P

Seeded From UniProt

complete

DANRE:Q7T2W1

involved_in

GO:0030902: hindbrain development

ECO:0000315: mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050607-2

P

Seeded From UniProt

complete

DANRE:Q7T2W1

involved_in

GO:0030902: hindbrain development

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-050607-2

P

Seeded From UniProt

complete

DANRE:Q7T2W1

involved_in

GO:0016055: Wnt signaling pathway

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-041217-12,ZFIN:ZDB-MRPHLNO-041217-13,ZFIN:ZDB-MRPHLNO-050607-2

P

Seeded From UniProt

complete

DANRE:Q7T2W1

involved_in

GO:0048332: mesoderm morphogenesis

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050607-2,ZFIN:ZDB-MRPHLNO-050901-1

P

Seeded From UniProt

complete

DANRE:Q90XF6

involved_in

GO:0048332: mesoderm morphogenesis

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-050607-2,ZFIN:ZDB-MRPHLNO-050901-1

P

Seeded From UniProt

complete

DANRE:WNT8A

involved_in

GO:0030902: hindbrain development

ECO:0000316: genetic interaction evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-041217-12
ZFIN:ZDB-MRPHLNO-041217-13
ZFIN:ZDB-MRPHLNO-050607-2

P

Seeded From UniProt

complete

DANRE:WNT8A

involved_in

GO:0030902: hindbrain development

ECO:0000315: mutant phenotype evidence used in manual assertion

ZFIN:ZDB-MRPHLNO-041217-12
ZFIN:ZDB-MRPHLNO-041217-13

P

Seeded From UniProt

complete

See also

References

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