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PMID:15609091

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Citation

Taguchi, M and Otsuki, M (2004) Co-localization of nestin and PDX-1 in small evaginations of the main pancreatic duct in adult rats. J. Mol. Histol. 35:785-9

Abstract

Pancreatic stem cells are powerful tools for future gene/cell therapy for diabetes, pancreatic carcinoma and chronic pancreatitis. However, it is unclear where the pancreatic stem cells exist in adult pancreas. To identify the pancreatic stem cells, we have focused on a homeodomain-containing transcription factor, pancreatic/duodenal homeobox-1 (PDX-1), and an intermediate filament protein, nestin, which are important candidates of pancreatic stem cell markers.

Links

PubMed Online version:10.1007/s10735-004-0948-9

Keywords

Animals; Biomarkers; Homeodomain Proteins/metabolism; Intermediate Filament Proteins/metabolism; Male; Nerve Tissue Proteins/metabolism; Nestin; Pancreatic Ducts/cytology; Pancreatic Ducts/metabolism; Rats; Rats, Wistar; Stem Cells/cytology; Stem Cells/physiology; Trans-Activators/metabolism

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

RAT:PDX1

colocalizes_with

GO:0005737: cytoplasm

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

Notes

See also

References

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