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PMID:15296748

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Citation

Kraut, R and Zinn, K (2004) Roundabout 2 regulates migration of sensory neurons by signaling in trans. Curr. Biol. 14:1319-29

Abstract

Roundabout (Robo) receptors and their ligand Slit are important regulators of axon guidance and cell migration. The development of Drosophila embryonic sense organs provides a neuronal migration paradigm where the in vivo roles of Slit and Robo can be assayed using genetics.

Links

PubMed Online version:10.1016/j.cub.2004.07.052

Keywords

Animals; Axons/physiology; Body Patterning/physiology; Cell Movement/physiology; Drosophila/embryology; Drosophila/metabolism; Drosophila Proteins/metabolism; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Luminescent Proteins; Mechanoreceptors/metabolism; Models, Biological; Nerve Tissue Proteins/metabolism; Receptors, Immunologic/metabolism; Signal Transduction/physiology

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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