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PMID:14527345

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Citation

Kiger, AA, Baum, B, Jones, S, Jones, MR, Coulson, A, Echeverri, C and Perrimon, N (2003) A functional genomic analysis of cell morphology using RNA interference. J. Biol. 2:27

Abstract

The diversity of metazoan cell shapes is influenced by the dynamic cytoskeletal network. With the advent of RNA-interference (RNAi) technology, it is now possible to screen systematically for genes controlling specific cell-biological processes, including those required to generate distinct morphologies.

Links

PubMed PMC333409 Online version:10.1186/1475-4924-2-27

Keywords

Animals; Cell Line; Cell Shape/genetics; Cell Shape/physiology; Cytoskeleton/genetics; Drosophila/classification; Drosophila/cytology; Drosophila/genetics; Drosophila Proteins/genetics; Drosophila Proteins/physiology; Genes, Insect/genetics; Genes, Insect/physiology; Genome; Genomics/methods; Microscopy, Fluorescence/methods; Mutation/genetics; PTEN Phosphohydrolase; Phenotype; Phosphoric Monoester Hydrolases/genetics; Phosphoric Monoester Hydrolases/physiology; RNA Interference/physiology; RNA, Double-Stranded/genetics; RNA, Double-Stranded/physiology

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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