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PMID:14190241

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Citation

FINK, GR (1964) GENE-ENZYME RELATIONS IN HISTIDINE BIOSYNTHESIS IN YEAST. Science 146:525-7

Abstract

Each of the histidine mutants of Saccharomyces cerevisiae has been correlated with a particular step in histidine biosynthesis. The relations of the genes controlling histidine biosynthesis in yeast appear to be identical with those found in Neurospora and clearly distinct from those found in Salmonella.

Links

PubMed

Keywords

Amino Acids/metabolism; Enzymes; Genes; Histidine; Mutation; Neurospora; Research; Saccharomyces; Salmonella

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

YEAST:HIS1

involved_in

GO:0000105: histidine biosynthetic process

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

YEAST:HIS1

enables

GO:0003879: ATP phosphoribosyltransferase activity

ECO:0000315: mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

YEAST:HIS2

involved_in

GO:0000105: histidine biosynthetic process

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

YEAST:HIS7

involved_in

GO:0000105: histidine biosynthetic process

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

YEAST:HIS7

enables

GO:0004424: imidazoleglycerol-phosphate dehydratase activity

ECO:0000315: mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

YEAST:HIS8

involved_in

GO:0000105: histidine biosynthetic process

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

YEAST:HIS8

enables

GO:0004400: histidinol-phosphate transaminase activity

ECO:0000315: mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

YEAST:HIS5

involved_in

GO:0000105: histidine biosynthetic process

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

YEAST:HIS5

located_in

GO:0005737: cytoplasm

ECO:0000305: curator inference used in manual assertion

GO:0000105

C

Seeded From UniProt

complete

YEAST:HIS9

involved_in

GO:0000105: histidine biosynthetic process

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

YEAST:HIS9

enables

GO:0004401: histidinol-phosphatase activity

ECO:0000315: mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

YEAST:HIS4

involved_in

GO:0000105: histidine biosynthetic process

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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