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Lin, X, Qadota, H, Moerman, DG and Williams, BD (2003) C. elegans PAT-6/actopaxin plays a critical role in the assembly of integrin adhesion complexes in vivo. Curr. Biol. 13:922-32
The novel focal adhesion protein actopaxin includes tandem unconventional calponin homology (CH) domains and a less well-conserved N-terminal stretch. Dominant-negative studies have implicated actopaxin in focal adhesion formation.
Actinin; Animals; Caenorhabditis elegans/metabolism; Caenorhabditis elegans Proteins/metabolism; Chromosome Mapping; Cloning, Molecular; Focal Adhesions; Gene Expression Profiling; Immunoblotting; Integrins/metabolism; Membrane Proteins/metabolism; Microfilament Proteins/genetics; Microfilament Proteins/metabolism; Muscle Proteins/metabolism; Proteoglycans/metabolism; RNA Interference
|Gene product||Qualifier||GO ID||GO term name||Evidence Code||with/from||Aspect||Notes||Status|
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