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PMID:12416537

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Citation

Adab, K, Sayne, JR, Carlson, DS and Opperman, LA (2002) Tgf-beta1, Tgf-beta2, Tgf-beta3 and Msx2 expression is elevated during frontonasal suture morphogenesis and during active postnatal facial growth. Orthod Craniofac Res 5:227-37

Abstract

It is hypothesized that regulation of facial suture morphogenesis is similar to that of cranial sutures, with expression of similar regulatory molecules, governing suture formation and patency. The present study was designed to characterize the morphology of the frontonasal (FN) suture of the rat at different developmental stages and to investigate the presence and temporal-spatial expression of transforming growth factor-beta 1 (Tgf-beta1), Tgf-beta2, Tgf-beta3 and Msx2 mRNA within these structures.

Links

PubMed

Keywords

Animals; Cranial Sutures/embryology; Cranial Sutures/growth & development; Cranial Sutures/metabolism; DNA-Binding Proteins/biosynthesis; DNA-Binding Proteins/genetics; Frontal Bone/embryology; Frontal Bone/growth & development; Gene Expression; Homeodomain Proteins; Immunohistochemistry; Maxillofacial Development/genetics; Morphogenesis; Nasal Bone/embryology; Nasal Bone/growth & development; RNA, Messenger/analysis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta/biosynthesis; Transforming Growth Factor beta/genetics

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

RAT:TGFB2

involved_in

GO:0060364: frontal suture morphogenesis

ECO:0000270: expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

RAT:TGFB3

involved_in

GO:0060364: frontal suture morphogenesis

ECO:0000270: expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

RAT:TGFB1

involved_in

GO:0060364: frontal suture morphogenesis

ECO:0000270: expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

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