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PMID:11696322

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Citation

Feierbach, B and Chang, F (2001) Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division. Curr. Biol. 11:1656-65

Abstract

Both symmetric and asymmetric cell divisions are required for the generation of appropriate cell lineages during development. Wild-type Schizosaccharomyces pombe cells divide in a symmetric fashion to produce two similar rod-shaped daughter cells. Formins are proteins with conserved roles in cell polarity, cytokinesis, and the regulation of actin and microtubule cytoskeletons.

Links

PubMed

Keywords

Actins/metabolism; Actins/ultrastructure; Cell Cycle Proteins/isolation & purification; Cell Division; Cell Polarity; Interphase; Microtubules/ultrastructure; Mutation; Myosin Type V/isolation & purification; Protein-Serine-Threonine Kinases/isolation & purification; Schizosaccharomyces/cytology; Schizosaccharomyces/metabolism; Schizosaccharomyces pombe Proteins/genetics; Schizosaccharomyces pombe Proteins/metabolism; Spindle Apparatus

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

SCHPO:FOR3

involved_in

GO:0000226: microtubule cytoskeleton organization

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

SCHPO:FOR3

is_active_in

GO:0036391: medial cortex septin ring

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

SCHPO:FOR3

is_active_in

GO:0051285: cell cortex of cell tip

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

SCHPO:FOR3

is_active_in

GO:0031097: medial cortex

ECO:0000314: direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

SCHPO:FOR3

involved_in

GO:0051017: actin filament bundle assembly

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

SCHPO:FOR3

involved_in

GO:0061572: actin filament bundle organization

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

SCHPO:FOR3

involved_in

GO:0061245: establishment or maintenance of bipolar cell polarity

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

SCHPO:FOR3

involved_in

GO:0051017: actin filament bundle assembly

ECO:0000315: mutant phenotype evidence used in manual assertion

P

happens_during:(GO:0051329)

Seeded From UniProt

complete

SCHPO:FOR3

involved_in

GO:0071963: establishment or maintenance of cell polarity regulating cell shape

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

Notes

See also

References

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