GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

PMID:10952464

From GONUTS
Jump to: navigation, search
Citation

Rooman, I, Heremans, Y, Heimberg, H and Bouwens, L (2000) Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro. Diabetologia 43:907-14

Abstract

In adult pancreatic regeneration models exocrine acini are found to transdifferentiate to duct-like complexes. This has also been associated with the formation of new endocrine islet cells. We aimed to establish an in vitro model in which this transdifferentiation process is characterised and can be modulated.

Links

PubMed Online version:10.1007/s001250051468

Keywords

Animals; Cell Differentiation; Cells, Cultured; Homeodomain Proteins/genetics; Intermediate Filament Proteins/genetics; Keratin-20; Keratin-7; Keratins/genetics; Male; Pancreatic Ducts/cytology; Pancreatic Ducts/physiology; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases/genetics; Receptors, Growth Factor/genetics; Receptors, Vascular Endothelial Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators/genetics; Transcription Factors/genetics

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

RAT:PDX1

involved_in

GO:0060290: transdifferentiation

ECO:0000270: expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete


See also

References

See Help:References for how to manage references in GONUTS.