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PIG:TYB4
Contents
| Species (Taxon ID) | Sus scrofa (Pig). (9823) | |
| Gene Name(s) | TMSB4 | |
| Protein Name(s) | Thymosin beta-4
T beta-4 Hematopoietic system regulatory peptide Seraspenide | |
| External Links | ||
| UniProt | Q95274 | |
| EMBL | Z81195 DQ372079 | |
| RefSeq | NP_001038020.1 XP_005673463.1 | |
| UniGene | Ssc.95276 | |
| ProteinModelPortal | Q95274 | |
| SMR | Q95274 | |
| STRING | 9823.ENSSSCP00000012903 | |
| PaxDb | Q95274 | |
| PRIDE | Q95274 | |
| Ensembl | ENSSSCT00000013257 ENSSSCT00000033294 ENSSSCT00000036603 ENSSSCT00000036667 | |
| GeneID | 733606 | |
| KEGG | ssc:733606 | |
| CTD | 7114 | |
| eggNOG | NOG126035 | |
| GeneTree | ENSGT00390000007040 | |
| HOVERGEN | HBG012534 | |
| InParanoid | Q95274 | |
| KO | K05764 | |
| OrthoDB | EOG7TJ3MT | |
| Proteomes | UP000008227 | |
| GO | GO:0005856 GO:0005829 GO:0005634 GO:0030036 GO:0030334 GO:0042989 | |
| Gene3D | 1.20.5.520 | |
| InterPro | IPR001152 IPR016323 | |
| PANTHER | PTHR12021 | |
| Pfam | PF01290 | |
| PIRSF | PIRSF001828 | |
| ProDom | PD005116 | |
| SMART | SM00152 | |
| PROSITE | PS00500 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
ECO:0000314 |
C |
Figure 4A & 6. |
complete | |||||
| GO:0005634 |
nucleus |
ECO:0000314 |
C |
Figure 3 |
complete | |||||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042989 |
sequestering of actin monomers |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:3026988 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030334 |
regulation of cell migration |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:99510 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002280337 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003785 |
actin monomer binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:3026988 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:2001171 |
positive regulation of ATP biosynthetic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:2001028 |
positive regulation of endothelial cell chemotaxis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:2000483 |
negative regulation of interleukin-8 secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1905273 |
positive regulation of proton-transporting ATP synthase activity, rotational mechanism |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1903026 |
negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1901223 |
negative regulation of NIK/NF-kappaB signaling |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1901222 |
regulation of NIK/NF-kappaB signaling |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0050727 |
regulation of inflammatory response |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043536 |
positive regulation of blood vessel endothelial cell migration |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042989 |
sequestering of actin monomers |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0033209 |
tumor necrosis factor-mediated signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019899 |
enzyme binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007253 |
cytoplasmic sequestering of NF-kappaB |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003785 |
actin monomer binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P62328 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003785 |
actin monomer binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007015 |
actin filament organization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003779 |
actin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Huff, T et al. (2004) Nuclear localisation of the G-actin sequestering peptide thymosin beta4. J. Cell. Sci. 117 5333-41 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
a
c
n
- GO:2000483 ! negative regulation of interleukin-8 secretion
- GO:1901223 ! negative regulation of non-canonical NF-kappaB signal transduction
- GO:1903026 ! negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding
- GO:0032088 ! negative regulation of NF-kappaB transcription factor activity
- GO:0005634 ! nucleus
o
p
- GO:1905273 ! positive regulation of proton-transporting ATP synthase activity, rotational mechanism
- GO:2001028 ! positive regulation of endothelial cell chemotaxis
- GO:2001171 ! positive regulation of ATP biosynthetic process
- GO:0043536 ! positive regulation of blood vessel endothelial cell migration
r
