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MYCTU:A85A
Contents
| Species (Taxon ID) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332) | |
| Gene Name(s) | fbpA (synonyms: mpt44) | |
| Protein Name(s) | Diacylglycerol acyltransferase/mycolyltransferase Ag85A
DGAT Acyl-CoA:diacylglycerol acyltransferase Antigen 85 complex A 85A Ag85A Fibronectin-binding protein A Fbps A | |
| External Links | ||
| UniProt | P9WQP3 | |
| EMBL | M27016 U47335 GQ150314 AL123456 | |
| PIR | H70887 | |
| RefSeq | NP_218321.1 YP_006517301.1 | |
| PDB | 1SFR | |
| PDBsum | 1SFR | |
| ProteinModelPortal | P9WQP3 | |
| SMR | P9WQP3 | |
| GeneID | 13317428 886132 | |
| KEGG | mtu:Rv3804c mtv:RVBD_3804c | |
| TubercuList | Rv3804c | |
| OMA | GGHNAVW | |
| PhylomeDB | P9WQP3 | |
| Proteomes | UP000001584 | |
| GO | GO:0005618 GO:0005737 GO:0005576 GO:0005886 GO:0004144 GO:0016747 GO:0050348 GO:0044119 GO:0044121 GO:0008152 | |
| Gene3D | 3.40.50.1820 | |
| InterPro | IPR029058 IPR000801 IPR006311 | |
| Pfam | PF00756 | |
| SUPFAM | SSF53474 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0035375 |
zymogen binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005618 |
cell wall |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005618 |
cell wall |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
C |
Seeded From UniProt |
Missing: with/from | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044121 |
growth of symbiont in host organelle |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044119 |
growth of symbiont in host cell |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016747 |
transferase activity, transferring acyl groups other than amino-acyl groups |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005618 |
cell wall |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071769 |
mycolate cell wall layer assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001330645 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016747 |
transferase activity, transferring acyl groups other than amino-acyl groups |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001330645 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004144 |
diacylglycerol O-acyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050348 |
trehalose O-mycolyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016746 |
transferase activity, transferring acyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005618 |
cell wall |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Xolalpa, W et al. (2007) Identification of novel bacterial plasminogen-binding proteins in the human pathogen Mycobacterium tuberculosis. Proteomics 7 3332-41 PubMed GONUTS page
- ↑ Gu, S et al. (2003) Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain. Mol. Cell Proteomics 2 1284-96 PubMed GONUTS page
- ↑ Wolfe, LM et al. (2010) Proteomic definition of the cell wall of Mycobacterium tuberculosis. J. Proteome Res. 9 5816-26 PubMed GONUTS page
- ↑ Mawuenyega, KG et al. (2005) Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol. Biol. Cell 16 396-404 PubMed GONUTS page
- ↑ Braunstein, M et al. (2000) Identification of genes encoding exported Mycobacterium tuberculosis proteins using a Tn552'phoA in vitro transposition system. J. Bacteriol. 182 2732-40 PubMed GONUTS page
- ↑ Målen, H et al. (2007) Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics 7 1702-18 PubMed GONUTS page
- ↑ 7.0 7.1 Armitige, LY et al. (2000) Disruption of the genes encoding antigen 85A and antigen 85B of Mycobacterium tuberculosis H37Rv: effect on growth in culture and in macrophages. Infect. Immun. 68 767-78 PubMed GONUTS page
- ↑ Belisle, JT et al. (1997) Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis. Science 276 1420-2 PubMed GONUTS page
- ↑ Harth, G et al. (1996) Novel insights into the genetics, biochemistry, and immunocytochemistry of the 30-kilodalton major extracellular protein of Mycobacterium tuberculosis. Infect. Immun. 64 3038-47 PubMed GONUTS page
- ↑ Harth, G et al. (1997) High-level heterologous expression and secretion in rapidly growing nonpathogenic mycobacteria of four major Mycobacterium tuberculosis extracellular proteins considered to be leading vaccine candidates and drug targets. Infect. Immun. 65 2321-8 PubMed GONUTS page
- ↑ 11.0 11.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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