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MOUSE:ULK3

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Ulk3
Protein Name(s) Serine/threonine-protein kinase ULK3

Unc-51-like kinase 3

External Links
UniProt Q3U3Q1
EMBL AK004783
AK154642
CH466522
BC037093
BC151153
CCDS CCDS52809.1
RefSeq NP_082171.1
UniGene Mm.155877
ProteinModelPortal Q3U3Q1
SMR Q3U3Q1
BindingDB Q3U3Q1
ChEMBL CHEMBL3832
PhosphoSite Q3U3Q1
MaxQB Q3U3Q1
PaxDb Q3U3Q1
PRIDE Q3U3Q1
Ensembl ENSMUST00000053230
GeneID 71742
KEGG mmu:71742
UCSC uc009pvf.2
CTD 25989
MGI MGI:1918992
eggNOG COG0515
GeneTree ENSGT00770000120504
HOGENOM HOG000233016
HOVERGEN HBG094133
InParanoid Q3U3Q1
KO K08269
OMA QQCLGEL
OrthoDB EOG71G9VJ
PhylomeDB Q3U3Q1
TreeFam TF324551
NextBio 334377
PRO PR:Q3U3Q1
Proteomes UP000000589
Bgee Q3U3Q1
CleanEx MM_ULK3
Genevestigator Q3U3Q1
GO GO:0034273
GO:0005737
GO:0005829
GO:0016020
GO:0000407
GO:0005524
GO:0004674
GO:0000045
GO:0045879
GO:0045880
GO:0046777
GO:0010506
Gene3D 1.20.58.280
InterPro IPR011009
IPR007330
IPR000719
IPR017441
IPR002290
IPR008271
Pfam PF04212
PF00069
SMART SM00745
SM00220
SUPFAM SSF116846
SSF56112
PROSITE PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0046777

protein autophosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6PHR2

P

Seeded From UniProt

complete

involved_in

GO:0045880

positive regulation of smoothened signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6PHR2

P

Seeded From UniProt

complete

involved_in

GO:0045879

negative regulation of smoothened signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6PHR2

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6PHR2

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6PHR2

F

Seeded From UniProt

complete

involved_in

GO:0046777

protein autophosphorylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260945
MGI:MGI:1270126
PANTHER:PTN000681272
SGD:S000003148
UniProtKB:O75385
UniProtKB:Q6PHR2
UniProtKB:Q8IYT8
WB:WBGene00006786
dictyBase:DDB_G0292390

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1270126
PANTHER:PTN000681272

C

Seeded From UniProt

complete

involved_in

GO:0010506

regulation of autophagy

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260945
PANTHER:PTN000681272

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1270126
PANTHER:PTN000681272
SGD:S000003148
UniProtKB:O75385

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0260945
MGI:MGI:1270126
MGI:MGI:1352758
PANTHER:PTN000681272
SGD:S000003148
UniProtKB:O75385
UniProtKB:Q6PHR2
UniProtKB:Q8IYT8

F

Seeded From UniProt

complete

part_of

GO:0000407

phagophore assembly site

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1270126
PANTHER:PTN000681272
PomBase:SPCC63.08c
SGD:S000003148

C

Seeded From UniProt

complete

involved_in

GO:0000045

autophagosome assembly

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1270126
PANTHER:PTN000681272
SGD:S000003148

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046777

protein autophosphorylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q6PHR2

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045880

positive regulation of smoothened signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q6PHR2

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045879

negative regulation of smoothened signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q6PHR2

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q6PHR2

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q6PHR2

F

Seeded From UniProt

complete

involved_in

GO:0046777

protein autophosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6PHR2
ensembl:ENSP00000400312

P

Seeded From UniProt

complete

involved_in

GO:0045880

positive regulation of smoothened signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6PHR2
ensembl:ENSP00000400312

P

Seeded From UniProt

complete

involved_in

GO:0045879

negative regulation of smoothened signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6PHR2
ensembl:ENSP00000400312

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6PHR2
ensembl:ENSP00000400312

C

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6PHR2
ensembl:ENSP00000400312

F

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0006914

autophagy

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0072

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page