GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MOUSE:TBX4
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Tbx4 | |
| Protein Name(s) | T-box transcription factor TBX4
T-box protein 4 | |
| External Links | ||
| UniProt | P70325 | |
| EMBL | AY075134 AL592465 CH466556 U57329 | |
| CCDS | CCDS25196.1 | |
| PIR | S72230 | |
| RefSeq | NP_035666.2 XP_006532843.1 | |
| UniGene | Mm.275336 | |
| ProteinModelPortal | P70325 | |
| SMR | P70325 | |
| BioGrid | 203989 | |
| STRING | 10090.ENSMUSP00000000096 | |
| PhosphoSite | P70325 | |
| PaxDb | P70325 | |
| PRIDE | P70325 | |
| Ensembl | ENSMUST00000000096 ENSMUST00000108047 | |
| GeneID | 21387 | |
| KEGG | mmu:21387 | |
| UCSC | uc007ksc.2 | |
| CTD | 9496 | |
| MGI | MGI:102556 | |
| eggNOG | NOG320009 | |
| GeneTree | ENSGT00760000118897 | |
| HOGENOM | HOG000286001 | |
| HOVERGEN | HBG007310 | |
| InParanoid | P70325 | |
| KO | K10178 | |
| OMA | CLKRRAD | |
| OrthoDB | EOG7GN2PM | |
| NextBio | 300630 | |
| PRO | PR:P70325 | |
| Proteomes | UP000000589 | |
| Bgee | P70325 | |
| CleanEx | MM_TBX4 | |
| ExpressionAtlas | P70325 | |
| Genevestigator | P70325 | |
| GO | GO:0005634 GO:0003677 GO:0003700 GO:0001525 GO:0030326 GO:0035108 GO:0030324 GO:0002009 GO:0048705 GO:0006351 | |
| Gene3D | 2.60.40.820 | |
| InterPro | IPR008967 IPR001699 IPR018186 | |
| PANTHER | PTHR11267 | |
| Pfam | PF00907 | |
| PRINTS | PR00937 | |
| SMART | SM00425 | |
| SUPFAM | SSF49417 | |
| PROSITE | PS01283 PS01264 PS50252 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0048705 |
skeletal system morphogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035108 |
limb morphogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0048705 |
skeletal system morphogenesis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0035108 |
limb morphogenesis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0035108 |
limb morphogenesis |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0030326 |
embryonic limb morphogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2663716 |
P |
has_participant:(EMAPA:16405) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0030324 |
lung development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0002009 |
morphogenesis of an epithelium |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0001525 |
angiogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2663716 |
P |
has_participant:(EMAPA:16107) |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0048705 |
skeletal system morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P57082 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035108 |
limb morphogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P57082 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001699 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001699 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Yi, CH et al. (2000) Virtual cloning and physical mapping of a human T-box gene, TBX4. Genomics 67 92-5 PubMed GONUTS page
- ↑ Minguillon, C et al. (2005) Tbx5 and Tbx4 are not sufficient to determine limb-specific morphologies but have common roles in initiating limb outgrowth. Dev. Cell 8 75-84 PubMed GONUTS page
- ↑ 3.0 3.1 Naiche, LA & Papaioannou, VE (2003) Loss of Tbx4 blocks hindlimb development and affects vascularization and fusion of the allantois. Development 130 2681-93 PubMed GONUTS page
- ↑ 4.0 4.1 Cebra-Thomas, JA et al. (2003) T-box gene products are required for mesenchymal induction of epithelial branching in the embryonic mouse lung. Dev. Dyn. 226 82-90 PubMed GONUTS page
