MOUSE:SYPH

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Syp
Protein Name(s)	Synaptophysin BM89 antigen Major synaptic vesicle protein p38
External Links
UniProt	Q62277
EMBL	AK043756 X95818 BC014823
CCDS	CCDS29967.2
RefSeq	NP_033331.2
UniGene	Mm.223674
ProteinModelPortal	Q62277
BioGrid	203609
IntAct	Q62277
MINT	MINT-4136497
PhosphoSite	Q62277
MaxQB	Q62277
PaxDb	Q62277
PRIDE	Q62277
Ensembl	ENSMUST00000069520
GeneID	20977
KEGG	mmu:20977
UCSC	uc009slr.2
CTD	6855
MGI	MGI:98467
eggNOG	NOG82723
GeneTree	ENSGT00390000010039
HOGENOM	HOG000252913
HOVERGEN	HBG006681
InParanoid	Q62277
OMA	AYGDAGY
OrthoDB	EOG7WT43S
PhylomeDB	Q62277
TreeFam	TF315804
ChiTaRS	Syp
NextBio	299960
PRO	PR:Q62277
Proteomes	UP000000589
Bgee	Q62277
CleanEx	MM_SYP
Genevestigator	Q62277
GO	GO:0030054 GO:0060076 GO:0030285 GO:0016020 GO:0043005 GO:0044306 GO:0048786 GO:0042734 GO:0043234 GO:0045202 GO:0008021 GO:0030672 GO:0015485 GO:0042802 GO:0042169 GO:0017075 GO:0005215 GO:0071310 GO:0006897 GO:0048169 GO:2000474 GO:0048172 GO:0007268
InterPro	IPR008253 IPR001285 IPR028714
PANTHER	PTHR10306 PTHR10306:SF10
Pfam	PF01284
PRINTS	PR00220
PROSITE	PS51225 PS00604

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0043005	neuron projection	PMID:21664258^[1]	ECO:0000315			C		Figure 2A- from Synaptosomal fraction found in presynaptic fraction of wild type and adult heterozygous reeler mice.	complete CACAO 2361
	GO:0042734	presynaptic membrane	PMID:21664258^[1]	ECO:0000269			C		Figure 2A- from Synaptosomal fraction found in presynaptic fraction of wild type and adult heterozygous reeler mice.	complete
	GO:0043025	neuronal cell body	PMID:3143927^[2]	ECO:0000314			C		Figure 4 uses immunofluorescence to show that synaptophysin is located in a neuronal soma in the golgi apparatus.	complete CACAO 10371
involved_in	GO:0048488	synaptic vesicle endocytosis	PMID:21658579^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0002608)	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:21664258^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:21307259^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002609)	Seeded From UniProt	complete
part_of	GO:0048786	presynaptic active zone	PMID:21664258^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:2000474	regulation of opioid receptor signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07825	P		Seeded From UniProt	complete
involved_in	GO:0048172	regulation of short-term neuronal synaptic plasticity	PMID:10595519^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048169	regulation of long-term neuronal synaptic plasticity	PMID:10595519^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0042734	presynaptic membrane	PMID:19506089^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P07825	P		Seeded From UniProt	complete
involved_in	GO:2000300	regulation of synaptic vesicle exocytosis	PMID:10595519^[5]	ECO:0006013	patch-clamp recording evidence used in manual assertion		P	occurs_in:(GO:0098685) occurs_in:(UBERON:0000061)	Seeded From UniProt	complete
involved_in	GO:2000300	regulation of synaptic vesicle exocytosis	PMID:10595519^[5]	ECO:0001225	knockout evidence used in manual assertion		P	occurs_in:(GO:0098685) occurs_in:(UBERON:0000061)	Seeded From UniProt	complete
part_of	GO:0098685	Schaffer collateral - CA1 synapse	PMID:10595519^[5]	ECO:0006013	patch-clamp recording evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0098685	Schaffer collateral - CA1 synapse	PMID:10595519^[5]	ECO:0001225	knockout evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0048786	presynaptic active zone	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98467 PANTHER:PTN002568989 RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0030672	synaptic vesicle membrane	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98467 PANTHER:PTN000033897 RGD:1359569 RGD:3802 RGD:708366	C		Seeded From UniProt	complete
enables	GO:0017075	syntaxin-1 binding	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000033897 RGD:3802	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000474	regulation of opioid receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071310	cellular response to organic substance	PMID:18497889^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0060076	excitatory synapse	PMID:16980967^[9]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002608)	Seeded From UniProt	complete
part_of	GO:0060076	excitatory synapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0048786	presynaptic active zone	PMID:17310244^[10]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P07825	C		Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	PMID:17046993^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:23986251^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:23704327^[13]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000210)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:18706977^[14]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:17168)\|part_of:(EMAPA:35610)\|part_of:(EMAPA:35607)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:18279309^[15]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:35741)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:17823315^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:17018287^[17]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:14622577^[18]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:12533614^[19]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:12368914^[20]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:10995443^[21]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:10712642^[22]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:32845) part_of:(CL:0000540)	Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	F		Seeded From UniProt	complete
part_of	GO:0044309	neuron spine	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0044306	neuron projection terminus	PMID:12115694^[23]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:35744) part_of:(CL:0000287)	Seeded From UniProt	complete
part_of	GO:0044306	neuron projection terminus	PMID:12074840^[24]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:19037) part_of:(CL:0000540)	Seeded From UniProt	complete
part_of	GO:0044306	neuron projection terminus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0043229	intracellular organelle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0043195	terminal bouton	PMID:29350434^[25]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043195	terminal bouton	PMID:20203623^[26]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:32845)	Seeded From UniProt	complete
part_of	GO:0043195	terminal bouton	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08247	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	PMID:18706977^[14]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q62277	F		Seeded From UniProt	complete
part_of	GO:0042734	presynaptic membrane	PMID:15328414^[27]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:19151) part_of:(CL:0000601)	Seeded From UniProt	complete
enables	GO:0042169	SH2 domain binding	PMID:18706977^[14]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0031594	neuromuscular junction	PMID:20826656^[28]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030672	synaptic vesicle membrane	PMID:15071120^[29]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030672	synaptic vesicle membrane	PMID:12805290^[30]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030672	synaptic vesicle membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0030285	integral component of synaptic vesicle membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	F		Seeded From UniProt	complete
enables	GO:0017075	syntaxin-1 binding	PMID:7553862^[31]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P07825	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:18706977^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:15748150^[32]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0015485	cholesterol binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P08247	F		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	PMID:9364068^[33]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	PMID:21884692^[34]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	PMID:17360631^[35]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	PMID:16407767^[36]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16894)	Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	PMID:12202822^[37]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	PMID:11879655^[38]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	PMID:12928441^[39]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P07825	C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006897	endocytosis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	P		Seeded From UniProt	complete
enables	GO:0000149	SNARE binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3802	F		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08247 ensembl:ENSP00000263233	C		Seeded From UniProt	complete
enables	GO:0015485	cholesterol binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P08247 ensembl:ENSP00000263233	F		Seeded From UniProt	complete
part_of	GO:0043195	terminal bouton	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A0A0G2KAD8 ensembl:ENSRNOP00000075360	C		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001285	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001285 InterPro:IPR008253	C		Seeded From UniProt	complete
involved_in	GO:0048168	regulation of neuronal synaptic plasticity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028714	P		Seeded From UniProt	complete
part_of	GO:0030285	integral component of synaptic vesicle membrane	PMID:12271488^[40]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007268	chemical synaptic transmission	PMID:12271488^[40]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006897	endocytosis	PMID:12271488^[40]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0771 UniProtKB-SubCell:SL-0261	C		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770	C		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C		Seeded From UniProt	complete
part_of	GO:0030672	synaptic vesicle membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0260	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Ventruti, A et al. (2011) Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain. Neuroscience 189 32-42 PubMed GONUTS page
↑ Tixier-Vidal, A et al. (1988) Immunoelectron microscopic localization of synaptophysin in a Golgi subcompartment of developing hypothalamic neurons. Neuroscience 26 847-61 PubMed GONUTS page
↑ Kwon, SE & Chapman, ER (2011) Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 70 847-54 PubMed GONUTS page
↑ Piccoli, G et al. (2011) LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J. Neurosci. 31 2225-37 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Janz, R et al. (1999) Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron 24 687-700 PubMed GONUTS page
↑ Stephenson, DT et al. (2009) Immunohistochemical localization of phosphodiesterase 2A in multiple mammalian species. J. Histochem. Cytochem. 57 933-49 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Pickford, F et al. (2008) The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J. Clin. Invest. 118 2190-9 PubMed GONUTS page
↑ Kim, S et al. (2006) NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Nat. Neurosci. 9 1294-301 PubMed GONUTS page
↑ Segura, I et al. (2007) Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nat. Neurosci. 10 301-10 PubMed GONUTS page
↑ Sun-Wada, GH et al. (2006) The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells. J. Cell. Sci. 119 4531-40 PubMed GONUTS page
↑ Nakanishi, N et al. (2013) Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites. J. Neurosci. 33 14170-83 PubMed GONUTS page
↑ Papal, S et al. (2013) The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route. Hum. Mol. Genet. 22 3773-88 PubMed GONUTS page
↑ ^14.0 ^14.1 ^14.2 ^14.3 Felkl, M & Leube, RE (2008) Interaction assays in yeast and cultured cells confirm known and identify novel partners of the synaptic vesicle protein synaptophysin. Neuroscience 156 344-52 PubMed GONUTS page
↑ Junghans, D et al. (2008) Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur. J. Neurosci. 27 559-71 PubMed GONUTS page
↑ Tabuchi, K et al. (2007) A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 318 71-6 PubMed GONUTS page
↑ Offenhäuser, N et al. (2006) Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell 127 213-26 PubMed GONUTS page
↑ Bamji, SX et al. (2003) Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. Neuron 40 719-31 PubMed GONUTS page
↑ Brandon, EP et al. (2003) Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. J. Neurosci. 23 539-49 PubMed GONUTS page
↑ Wilson, SM et al. (2002) Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease. Nat. Genet. 32 420-5 PubMed GONUTS page
↑ Adams, ME et al. (2000) Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin. J. Cell Biol. 150 1385-98 PubMed GONUTS page
↑ Pellet, JB et al. (2000) Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain. Eur. J. Neurosci. 12 621-32 PubMed GONUTS page
↑ Jellali, A et al. (2002) Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina. J. Comp. Neurol. 449 76-87 PubMed GONUTS page
↑ Fukami, S et al. (2002) Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology. Neurosci. Res. 43 39-56 PubMed GONUTS page
↑ Ottestad-Hansen, S et al. (2018) The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain. Glia 66 951-970 PubMed GONUTS page
↑ Glyvuk, N et al. (2010) AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. EMBO J. 29 1318-30 PubMed GONUTS page
↑ Rüttiger, L et al. (2004) Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proc. Natl. Acad. Sci. U.S.A. 101 12922-7 PubMed GONUTS page
↑ Hideyama, T et al. (2010) Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2. J. Neurosci. 30 11917-25 PubMed GONUTS page
↑ Gitler, D et al. (2004) Molecular determinants of synapsin targeting to presynaptic terminals. J. Neurosci. 24 3711-20 PubMed GONUTS page
↑ Pigino, G et al. (2003) Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport. J. Neurosci. 23 4499-508 PubMed GONUTS page
↑ McMahon, HT et al. (1995) Complexins: cytosolic proteins that regulate SNAP receptor function. Cell 83 111-9 PubMed GONUTS page
↑ Trinidad, JC et al. (2005) Phosphorylation state of postsynaptic density proteins. J. Neurochem. 92 1306-16 PubMed GONUTS page
↑ Shibata, T et al. (1997) Glutamate transporter GLAST is expressed in the radial glia-astrocyte lineage of developing mouse spinal cord. J. Neurosci. 17 9212-9 PubMed GONUTS page
↑ Richard, AF et al. (2011) Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev. Biol. 359 303-20 PubMed GONUTS page
↑ Ikegami, K et al. (2007) Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function. Proc. Natl. Acad. Sci. U.S.A. 104 3213-8 PubMed GONUTS page
↑ Fukuda, M (2006) Distinct developmental expression of synaptotagmin I and IX in the mouse brain. Neuroreport 17 179-82 PubMed GONUTS page
↑ Biederer, T et al. (2002) SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science 297 1525-31 PubMed GONUTS page
↑ Di Paolo, G et al. (2002) Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron 33 789-804 PubMed GONUTS page
↑ Belfort, GM & Kandror, KV (2003) Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells. J. Biol. Chem. 278 47971-8 PubMed GONUTS page
↑ ^40.0 ^40.1 ^40.2 Singec, I et al. (2002) Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons. J. Comp. Neurol. 452 139-53 PubMed GONUTS page

[PMID:21664258-1] 1.0 ^1.1 ^1.2 ^1.3 Ventruti, A et al. (2011) Reelin deficiency causes specific defects in the molecular composition of the synapses in the adult brain. Neuroscience 189 32-42 PubMed GONUTS page

[PMID:3143927-2] Tixier-Vidal, A et al. (1988) Immunoelectron microscopic localization of synaptophysin in a Golgi subcompartment of developing hypothalamic neurons. Neuroscience 26 847-61 PubMed GONUTS page

[PMID:21658579-3] Kwon, SE & Chapman, ER (2011) Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 70 847-54 PubMed GONUTS page

[PMID:21307259-4] Piccoli, G et al. (2011) LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J. Neurosci. 31 2225-37 PubMed GONUTS page

[PMID:10595519-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Janz, R et al. (1999) Essential roles in synaptic plasticity for synaptogyrin I and synaptophysin I. Neuron 24 687-700 PubMed GONUTS page

[PMID:19506089-6] Stephenson, DT et al. (2009) Immunohistochemical localization of phosphodiesterase 2A in multiple mammalian species. J. Histochem. Cytochem. 57 933-49 PubMed GONUTS page

[PMID:21873635-7] 7.0 ^7.1 ^7.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:18497889-8] Pickford, F et al. (2008) The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J. Clin. Invest. 118 2190-9 PubMed GONUTS page

[PMID:16980967-9] Kim, S et al. (2006) NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Nat. Neurosci. 9 1294-301 PubMed GONUTS page

[PMID:17310244-10] Segura, I et al. (2007) Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nat. Neurosci. 10 301-10 PubMed GONUTS page

[PMID:17046993-11] Sun-Wada, GH et al. (2006) The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cells. J. Cell. Sci. 119 4531-40 PubMed GONUTS page

[PMID:23986251-12] Nakanishi, N et al. (2013) Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites. J. Neurosci. 33 14170-83 PubMed GONUTS page

[PMID:23704327-13] Papal, S et al. (2013) The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route. Hum. Mol. Genet. 22 3773-88 PubMed GONUTS page

[PMID:18706977-14] 14.0 ^14.1 ^14.2 ^14.3 Felkl, M & Leube, RE (2008) Interaction assays in yeast and cultured cells confirm known and identify novel partners of the synaptic vesicle protein synaptophysin. Neuroscience 156 344-52 PubMed GONUTS page

[PMID:18279309-15] Junghans, D et al. (2008) Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system. Eur. J. Neurosci. 27 559-71 PubMed GONUTS page

[PMID:17823315-16] Tabuchi, K et al. (2007) A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 318 71-6 PubMed GONUTS page

[PMID:17018287-17] Offenhäuser, N et al. (2006) Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell 127 213-26 PubMed GONUTS page

[PMID:14622577-18] Bamji, SX et al. (2003) Role of beta-catenin in synaptic vesicle localization and presynaptic assembly. Neuron 40 719-31 PubMed GONUTS page

[PMID:12533614-19] Brandon, EP et al. (2003) Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. J. Neurosci. 23 539-49 PubMed GONUTS page

[PMID:12368914-20] Wilson, SM et al. (2002) Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific protease. Nat. Genet. 32 420-5 PubMed GONUTS page

[PMID:10995443-21] Adams, ME et al. (2000) Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin. J. Cell Biol. 150 1385-98 PubMed GONUTS page

[PMID:10712642-22] Pellet, JB et al. (2000) Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain. Eur. J. Neurosci. 12 621-32 PubMed GONUTS page

[PMID:12115694-23] Jellali, A et al. (2002) Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina. J. Comp. Neurol. 449 76-87 PubMed GONUTS page

[PMID:12074840-24] Fukami, S et al. (2002) Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology. Neurosci. Res. 43 39-56 PubMed GONUTS page

[PMID:29350434-25] Ottestad-Hansen, S et al. (2018) The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain. Glia 66 951-970 PubMed GONUTS page

[PMID:20203623-26] Glyvuk, N et al. (2010) AP-1/sigma1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. EMBO J. 29 1318-30 PubMed GONUTS page

[PMID:15328414-27] Rüttiger, L et al. (2004) Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proc. Natl. Acad. Sci. U.S.A. 101 12922-7 PubMed GONUTS page

[PMID:20826656-28] Hideyama, T et al. (2010) Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2. J. Neurosci. 30 11917-25 PubMed GONUTS page

[PMID:15071120-29] Gitler, D et al. (2004) Molecular determinants of synapsin targeting to presynaptic terminals. J. Neurosci. 24 3711-20 PubMed GONUTS page

[PMID:12805290-30] Pigino, G et al. (2003) Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport. J. Neurosci. 23 4499-508 PubMed GONUTS page

[PMID:7553862-31] McMahon, HT et al. (1995) Complexins: cytosolic proteins that regulate SNAP receptor function. Cell 83 111-9 PubMed GONUTS page

[PMID:15748150-32] Trinidad, JC et al. (2005) Phosphorylation state of postsynaptic density proteins. J. Neurochem. 92 1306-16 PubMed GONUTS page

[PMID:9364068-33] Shibata, T et al. (1997) Glutamate transporter GLAST is expressed in the radial glia-astrocyte lineage of developing mouse spinal cord. J. Neurosci. 17 9212-9 PubMed GONUTS page

[PMID:21884692-34] Richard, AF et al. (2011) Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev. Biol. 359 303-20 PubMed GONUTS page

[PMID:17360631-35] Ikegami, K et al. (2007) Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function. Proc. Natl. Acad. Sci. U.S.A. 104 3213-8 PubMed GONUTS page

[PMID:16407767-36] Fukuda, M (2006) Distinct developmental expression of synaptotagmin I and IX in the mouse brain. Neuroreport 17 179-82 PubMed GONUTS page

[PMID:12202822-37] Biederer, T et al. (2002) SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science 297 1525-31 PubMed GONUTS page

[PMID:11879655-38] Di Paolo, G et al. (2002) Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice. Neuron 33 789-804 PubMed GONUTS page

[PMID:12928441-39] Belfort, GM & Kandror, KV (2003) Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells. J. Biol. Chem. 278 47971-8 PubMed GONUTS page

[PMID:12271488-40] 40.0 ^40.1 ^40.2 Singec, I et al. (2002) Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons. J. Comp. Neurol. 452 139-53 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

[17]

[18]

[19]

[20]

[21]

[22]

[23]

[24]

[25]

[26]

[27]

[28]

[29]

[30]

[31]

[32]

[33]

[34]

[35]

[36]

[37]

[38]

[39]

[40]

MOUSE:SYPH

Contents

Annotations

Notes

References

c

e

g

i

m

n

o

p

r

s

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools