MOUSE:ST2B1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Sult2b1 (synonyms: Sult2b)
Protein Name(s)	Sulfotransferase family cytosolic 2B member 1 ST2B1 Sulfotransferase 2B1 Alcohol sulfotransferase Hydroxysteroid sulfotransferase 2
External Links
UniProt	O35400
EMBL	AF026072 AF478566 BC009811 BC009813
CCDS	CCDS21263.1
PIR	JE0196
RefSeq	NP_059493.2
UniGene	Mm.271634
ProteinModelPortal	O35400
SMR	O35400
IntAct	O35400
PhosphoSite	O35400
MaxQB	O35400
PaxDb	O35400
PRIDE	O35400
Ensembl	ENSMUST00000075571
GeneID	54200
KEGG	mmu:54200
UCSC	uc009gxb.2
CTD	6820
MGI	MGI:1926342
eggNOG	NOG296990
GeneTree	ENSGT00760000118932
HOGENOM	HOG000037209
HOVERGEN	HBG001195
InParanoid	O35400
KO	K01015
OrthoDB	EOG7V49ZK
PhylomeDB	O35400
TreeFam	TF321745
BRENDA	2.8.2.2
Reactome	REACT_241116
NextBio	311058
PRO	PR:O35400
Proteomes	UP000000589
Bgee	O35400
CleanEx	MM_SULT2B1
ExpressionAtlas	O35400
Genevestigator	O35400
GO	GO:0005783 GO:0004027 GO:0050294 GO:0008146 GO:0008202 GO:0000103
Gene3D	3.40.50.300
InterPro	IPR027417 IPR000863
Pfam	PF00685
SUPFAM	SSF52540

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0050294	steroid sulfotransferase activity	PMID:23674610^[1]	ECO:0000315			F	The evidence and experiment suggests necessary information about steroid sulfotransferase activity	complete CACAO 10593
part_of	GO:0005829	cytosol	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O00204	C	Seeded From UniProt	complete
involved_in	GO:0008203	cholesterol metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O00204	P	Seeded From UniProt	complete
enables	GO:1990239	steroid hormone binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	P	Seeded From UniProt	complete
enables	GO:0050294	steroid sulfotransferase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045606	positive regulation of epidermal cell differentiation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	P	Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	C	Seeded From UniProt	complete
enables	GO:0015485	cholesterol binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008285	negative regulation of cell population proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008203	cholesterol metabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008202	steroid metabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	P	Seeded From UniProt	complete
enables	GO:0008146	sulfotransferase activity	PMID:9647753^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	C	Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00204	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000103	sulfate assimilation	PMID:9647753^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:1990239	steroid hormone binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	F	Seeded From UniProt	complete
involved_in	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	P	Seeded From UniProt	complete
enables	GO:0050294	steroid sulfotransferase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	F	Seeded From UniProt	complete
involved_in	GO:0045606	positive regulation of epidermal cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	P	Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	C	Seeded From UniProt	complete
enables	GO:0015485	cholesterol binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	F	Seeded From UniProt	complete
involved_in	GO:0008285	negative regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	P	Seeded From UniProt	complete
involved_in	GO:0008203	cholesterol metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	P	Seeded From UniProt	complete
involved_in	GO:0008202	steroid metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	C	Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00204 ensembl:ENSP00000201586	F	Seeded From UniProt	complete
enables	GO:0008146	sulfotransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000863	F	Seeded From UniProt	complete
enables	GO:0004027	alcohol sulfotransferase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.8.2.2	F	Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0492 UniProtKB-SubCell:SL-0166	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
involved_in	GO:0008202	steroid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0753	P	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0443	P	Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0256	C	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0091	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Barrett, KG et al. (2013) Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency. Drug Metab. Dispos. 41 1505-13 PubMed GONUTS page
↑ ^2.0 ^2.1 Sakakibara, Y et al. (1998) Molecular cloning, expression, and functional characterization of novel mouse sulfotransferases. Biochem. Biophys. Res. Commun. 247 681-6 PubMed GONUTS page

[PMID:23674610-1] Barrett, KG et al. (2013) Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency. Drug Metab. Dispos. 41 1505-13 PubMed GONUTS page

[PMID:9647753-2] 2.0 ^2.1 Sakakibara, Y et al. (1998) Molecular cloning, expression, and functional characterization of novel mouse sulfotransferases. Biochem. Biophys. Res. Commun. 247 681-6 PubMed GONUTS page

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MOUSE:ST2B1

Contents

Annotations

Notes

References

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