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MOUSE:SPN90
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Nckipsd (synonyms: Spin90, Wasbp) | |
Protein Name(s) | NCK-interacting protein with SH3 domain
54 kDa VacA-interacting protein VIP54 90 kDa N-WASP-interacting protein 90 kDa SH3 protein interacting with Nck SH3 adapter protein SPIN90 WASP-interacting SH3-domain protein WISH Wiskott-Aldrich syndrome protein-binding protein N-WASP-binding protein | |
External Links | ||
UniProt | Q9ESJ4 | |
EMBL | AF130313 AK134725 CH466560 BC064818 | |
CCDS | CCDS23538.1 | |
RefSeq | NP_109654.2 | |
UniGene | Mm.192416 | |
ProteinModelPortal | Q9ESJ4 | |
SMR | Q9ESJ4 | |
BioGrid | 219860 | |
IntAct | Q9ESJ4 | |
MINT | MINT-157148 | |
PhosphoSite | Q9ESJ4 | |
MaxQB | Q9ESJ4 | |
PaxDb | Q9ESJ4 | |
PRIDE | Q9ESJ4 | |
Ensembl | ENSMUST00000035218 | |
GeneID | 80987 | |
KEGG | mmu:80987 | |
UCSC | uc009rqz.1 | |
CTD | 51517 | |
MGI | MGI:1931834 | |
eggNOG | NOG283973 | |
GeneTree | ENSGT00390000015725 | |
HOGENOM | HOG000008184 | |
HOVERGEN | HBG061630 | |
InParanoid | Q9ESJ4 | |
OMA | PATSSIM | |
OrthoDB | EOG7966G7 | |
PhylomeDB | Q9ESJ4 | |
TreeFam | TF324522 | |
Reactome | REACT_198374 | |
NextBio | 350330 | |
PRO | PR:Q9ESJ4 | |
Proteomes | UP000000589 | |
Bgee | Q9ESJ4 | |
CleanEx | MM_NCKIPSD | |
Genevestigator | Q9ESJ4 | |
GO | GO:0008180 | |
InterPro | IPR018556 IPR001452 | |
Pfam | PF09431 PF00018 | |
SMART | SM00326 | |
SUPFAM | SSF50044 | |
PROSITE | PS50002 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0040008 |
regulation of growth |
ECO:0000315 |
P |
Figure 4 - SPIN90 affects cytoskeleton organization by "regulating growth cone morphology" |
complete | |||||
involved_in |
GO:0010976 |
positive regulation of neuron projection development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
GO:0010976 |
positive regulation of neuron projection development |
ECO:0000315 |
P |
Figure 6. When SPIN90 was knocked out, neurite outgrowth was inhibited. This was shown by comparing the length of the longest neurite and the length of shorter neurites of wild-type and of SPIN90 knocked-out hippocampal neurons. |
complete | |||||
colocalizes_with |
GO:0008180 |
COP9 signalosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0008180 |
COP9 signalosome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9NZQ3 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0017124 |
SH3 domain binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Kim, SM et al. (2011) Control of growth cone motility and neurite outgrowth by SPIN90. Exp. Cell Res. 317 2276-87 PubMed GONUTS page
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