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MOUSE:SIL1

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Sil1
Protein Name(s) Nucleotide exchange factor SIL1
External Links
UniProt Q9EPK6
EMBL AJ297884
AK170415
BC016119
BC016466
CCDS CCDS29140.1
RefSeq NP_109674.2
XP_006526428.1
XP_006526429.1
UniGene Mm.291482
ProteinModelPortal Q9EPK6
SMR Q9EPK6
BioGrid 219881
IntAct Q9EPK6
MINT MINT-4128883
PhosphoSite Q9EPK6
MaxQB Q9EPK6
PaxDb Q9EPK6
PRIDE Q9EPK6
Ensembl ENSMUST00000025215
GeneID 81500
KEGG mmu:81500
UCSC uc008emc.2
CTD 64374
MGI MGI:1932040
eggNOG NOG310365
GeneTree ENSGT00510000048102
HOGENOM HOG000154326
HOVERGEN HBG093955
InParanoid Q9EPK6
KO K14001
OMA QGWCEIT
OrthoDB EOG72G176
PhylomeDB Q9EPK6
TreeFam TF324307
ChiTaRS Sil1
NextBio 350402
PRO PR:Q9EPK6
Proteomes UP000000589
Bgee Q9EPK6
Genevestigator Q9EPK6
GO GO:0005783
GO:0005788
GO:0005615
GO:0015031
Gene3D 1.25.10.10
InterPro IPR011989
IPR016024
SUPFAM SSF48371

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

Contributes to

GO:2001224

positive regulation of neuron migration

PMID:3958314[1]

ECO:0000315

P

in figure 4C. silencing SIL1 resulted in delay migration. Neuronal migration was monitored by pCAG-EGFP, which is a reporter and staining for GFP.

complete
CACAO 10830

part_of

GO:0005783

endoplasmic reticulum

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1932040
PANTHER:PTN000448398
TAIR:locus:2083800

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000448398
UniProtKB:Q84J81

C

Seeded From UniProt

complete

enables

GO:0000774

adenyl-nucleotide exchange factor activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000448398
SGD:S000000305
SGD:S000005391

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

PMID:16116427[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000121)

Seeded From UniProt

complete

involved_in

GO:0050790

regulation of catalytic activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0000774

P

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653
UniProtKB-KW:KW-0811

P

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

part_of

GO:0005788

endoplasmic reticulum lumen

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0096

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Thoms, EM & Robinson, WH (1986) Distribution, seasonal abundance, and pest status of the oriental cockroach (Orthoptera: Blattidae) and an evaniid wasp (Hymenoptera: Evaniidae) in urban apartments. J. Econ. Entomol. 79 431-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. Zhao, L et al. (2005) Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nat. Genet. 37 974-9 PubMed GONUTS page