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MOUSE:SACA3

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Spaca3 (synonyms: Lyc3, Lyzl3, Sllp1)
Protein Name(s) Sperm acrosome membrane-associated protein 3

Lysozyme-like protein 3 Sperm lysozyme-like protein 1 mSLLP1 Sperm acrosome membrane-associated protein 3, membrane form Sperm acrosome membrane-associated protein 3, processed form

External Links
UniProt Q9D9X8
EMBL AY572448
AK006357
AL645842
BC100503
AY601763
CCDS CCDS25136.1
RefSeq NP_083643.1
UniGene Mm.26988
PDB 2GOI
PDBsum 2GOI
ProteinModelPortal Q9D9X8
SMR Q9D9X8
CAZy GH22
PhosphoSite Q9D9X8
PaxDb Q9D9X8
Ensembl ENSMUST00000103222
ENSMUST00000103223
GeneID 75622
KEGG mmu:75622
UCSC uc007kmk.1
CTD 124912
MGI MGI:1922872
eggNOG NOG68773
GeneTree ENSGT00550000074398
HOGENOM HOG000037357
HOVERGEN HBG052297
InParanoid Q9D9X8
OMA GYWEAWR
OrthoDB EOG7BW0M5
PhylomeDB Q9D9X8
TreeFam TF324882
EvolutionaryTrace Q9D9X8
NextBio 343538
PRO PR:Q9D9X8
Proteomes UP000000589
Bgee Q9D9X8
CleanEx MM_SPACA3
Genevestigator Q9D9X8
GO GO:0002080
GO:0001669
GO:0005576
GO:0016021
GO:0005764
GO:0030141
GO:0003796
GO:0016998
GO:0035036
InterPro IPR001916
IPR019799
IPR000974
IPR023346
IPR030058
PANTHER PTHR11407:SF25
Pfam PF00062
PRINTS PR00137
PR00135
SMART SM00263
SUPFAM SSF53955
PROSITE PS00128
PS51348

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0007339

binding of sperm to zona pellucida

PMID:15982649[1]

ECO:0000314

P

Fig 7a & b. The table shows that the SLLP1 gene influences binding of the sperm to zona pellucida, but not fusion.

complete

involved_in

GO:0007342

fusion of sperm to egg plasma membrane involved in single fertilization

PMID:15982649[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030141

secretory granule

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8IXA5

C

Seeded From UniProt

complete

involved_in

GO:0050830

defense response to Gram-positive bacterium

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96897
MGI:MGI:96902
PANTHER:PTN000892307
RGD:3026
UniProtKB:P61626

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96897
MGI:MGI:96902
PANTHER:PTN000892307
RGD:1308401
RGD:3026

P

Seeded From UniProt

complete

part_of

GO:0043159

acrosomal matrix

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8IXA5

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0035036

sperm-egg recognition

PMID:15982649[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030141

secretory granule

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8IXA5

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007342

fusion of sperm to egg plasma membrane involved in single fertilization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8IXA5

P

Seeded From UniProt

complete

part_of

GO:0002080

acrosomal membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8IXA5

C

Seeded From UniProt

complete

part_of

GO:0001669

acrosomal vesicle

PMID:15982649[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0043159

acrosomal matrix

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8IXA5
ensembl:ENSP00000269053

C

Seeded From UniProt

complete

part_of

GO:0030141

secretory granule

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8IXA5
ensembl:ENSP00000269053

C

Seeded From UniProt

complete

involved_in

GO:0007342

fusion of sperm to egg plasma membrane involved in single fertilization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8IXA5
ensembl:ENSP00000269053

P

Seeded From UniProt

complete

part_of

GO:0002080

acrosomal membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8IXA5
ensembl:ENSP00000269053

C

Seeded From UniProt

complete

enables

GO:0003796

lysozyme activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000974

F

Seeded From UniProt

complete

involved_in

GO:0009566

fertilization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030058

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0968

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

part_of

GO:0002080

acrosomal membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0006

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Herrero, MB et al. (2005) Mouse SLLP1, a sperm lysozyme-like protein involved in sperm-egg binding and fertilization. Dev. Biol. 284 126-42 PubMed GONUTS page
  2. 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page