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MOUSE:RFWD2

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Rfwd2 (synonyms: Cop1)
Protein Name(s) E3 ubiquitin-protein ligase RFWD2

Constitutive photomorphogenesis protein 1 homolog mCOP1 RING finger and WD repeat domain protein 2

External Links
UniProt Q9R1A8
EMBL AF151110
BC082804
CCDS CCDS35745.1
RefSeq NP_036061.1
UniGene Mm.328135
ProteinModelPortal Q9R1A8
SMR Q9R1A8
BioGrid 204934
DIP DIP-60522N
STRING 10090.ENSMUSP00000085201
PhosphoSite Q9R1A8
MaxQB Q9R1A8
PaxDb Q9R1A8
PRIDE Q9R1A8
Ensembl ENSMUST00000076894
GeneID 26374
KEGG mmu:26374
UCSC uc007ddz.1
CTD 64326
MGI MGI:1347046
eggNOG COG2319
GeneTree ENSGT00570000079069
HOGENOM HOG000006123
HOVERGEN HBG054995
InParanoid Q9R1A8
KO K10143
OMA FSTRMTR
OrthoDB EOG75TMB6
PhylomeDB Q9R1A8
TreeFam TF328912
Reactome REACT_212633
UniPathway UPA00143
ChiTaRS Rfwd2
NextBio 304277
PRO PR:Q9R1A8
Proteomes UP000000589
Bgee Q9R1A8
CleanEx MM_RFWD2
Genevestigator Q9R1A8
GO GO:0005813
GO:0005925
GO:0000139
GO:0016607
GO:0016874
GO:0008270
GO:0016567
Gene3D 2.130.10.10
3.30.40.10
InterPro IPR015943
IPR001680
IPR019775
IPR017986
IPR018957
IPR001841
IPR013083
IPR017907
Pfam PF00400
PF00097
SMART SM00184
SM00320
SUPFAM SSF50978
PROSITE PS00678
PS50082
PS50294
PS00518
PS50089

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0061630

ubiquitin protein ligase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8NHY2

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8NHY2

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8NHY2

P

Seeded From UniProt

complete

part_of

GO:0031464

Cul4A-RING E3 ubiquitin ligase complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8NHY2

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010212

response to ionizing radiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8NHY2

P

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1304773

C

Seeded From UniProt

complete

enables

GO:0061630

ubiquitin protein ligase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8NHY2
ensembl:ENSP00000356641

F

Seeded From UniProt

complete

involved_in

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8NHY2
ensembl:ENSP00000356641

P

Seeded From UniProt

complete

involved_in

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8NHY2
ensembl:ENSP00000356641

P

Seeded From UniProt

complete

part_of

GO:0031464

Cul4A-RING E3 ubiquitin ligase complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8NHY2
ensembl:ENSP00000356641

C

Seeded From UniProt

complete

involved_in

GO:0010212

response to ionizing radiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8NHY2
ensembl:ENSP00000356641

P

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:A0A096UWG1
ensembl:ENSRNOP00000048511

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0016607

nuclear speck

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0186

C

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00143

P

Seeded From UniProt

complete

Notes

References

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