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MOUSE:KCNH1

From GONUTS
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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Kcnh1 (synonyms: Eag)
Protein Name(s) Potassium voltage-gated channel subfamily H member 1

Ether-a-go-go potassium channel 1 EAG channel 1 EAG1 m-eag Voltage-gated potassium channel subunit Kv10.1

External Links
UniProt Q60603
EMBL U04294
CCDS CCDS15627.1
PIR I48912
RefSeq NP_034730.1
UniGene Mm.4489
PDB 4F8A
4HOI
4LLO
PDBsum 4F8A
4HOI
4LLO
ProteinModelPortal Q60603
SMR Q60603
IntAct Q60603
PhosphoSite Q60603
PaxDb Q60603
PRIDE Q60603
Ensembl ENSMUST00000078470
GeneID 16510
KEGG mmu:16510
UCSC uc007edo.1
CTD 3756
MGI MGI:1341721
eggNOG COG2202
GeneTree ENSGT00760000118772
HOGENOM HOG000230794
HOVERGEN HBG101348
InParanoid Q60603
KO K04904
OMA HAKLHAP
OrthoDB EOG7QG43V
PhylomeDB Q60603
TreeFam TF313130
Reactome REACT_199077
NextBio 289847
PRO PR:Q60603
Proteomes UP000000589
Bgee Q60603
ExpressionAtlas Q60603
Genevestigator Q60603
GO GO:0005887
GO:0005637
GO:0000155
GO:0005249
GO:0071805
GO:0042391
Gene3D 2.60.120.10
InterPro IPR018490
IPR000595
IPR030170
IPR005821
IPR003949
IPR003938
IPR001610
IPR000014
IPR000700
IPR014710
PANTHER PTHR10217:SF377
Pfam PF00027
PF00520
PF13426
PRINTS PR01463
PR01464
SMART SM00100
SM00086
SM00091
SUPFAM SSF51206
SSF55785
TIGRFAMs TIGR00229
PROSITE PS50042
PS50113
PS50112

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:1902936

phosphatidylinositol bisphosphate binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

F

Seeded From UniProt

complete

involved_in

GO:0071277

cellular response to calcium ion

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

P

Seeded From UniProt

complete

involved_in

GO:0048015

phosphatidylinositol-mediated signaling

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:19671703[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

PMID:19671703[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005251

delayed rectifier potassium channel activity

PMID:19671703[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

NOT|enables

GO:0030551

cyclic nucleotide binding

PMID:19671703[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

C

Seeded From UniProt

complete

part_of

GO:0008076

voltage-gated potassium channel complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

C

Seeded From UniProt

complete

enables

GO:0005251

delayed rectifier potassium channel activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

F

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

P

Seeded From UniProt

complete

involved_in

GO:0042127

regulation of cell population proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

P

Seeded From UniProt

complete

part_of

GO:0031901

early endosome membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95259

C

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:25556795[2]

ECO:0006063

over expression analysis evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:25556795[2]

ECO:0006039

genetically encoded fluorescent electrophysiology assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:25556795[2]

ECO:0006013

patch-clamp recording evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:25556795[2]

ECO:0001225

knockout evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0099509

regulation of presynaptic cytosolic calcium ion concentration

PMID:25556795[2]

ECO:0006063

over expression analysis evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0099509

regulation of presynaptic cytosolic calcium ion concentration

PMID:25556795[2]

ECO:0006039

genetically encoded fluorescent electrophysiology assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0099509

regulation of presynaptic cytosolic calcium ion concentration

PMID:25556795[2]

ECO:0006013

patch-clamp recording evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0099509

regulation of presynaptic cytosolic calcium ion concentration

PMID:25556795[2]

ECO:0001225

knockout evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0099508

voltage-gated ion channel activity involved in regulation of presynaptic membrane potential

PMID:25556795[2]

ECO:0006063

over expression analysis evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0099508

voltage-gated ion channel activity involved in regulation of presynaptic membrane potential

PMID:25556795[2]

ECO:0006039

genetically encoded fluorescent electrophysiology assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0099508

voltage-gated ion channel activity involved in regulation of presynaptic membrane potential

PMID:25556795[2]

ECO:0006013

patch-clamp recording evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0099508

voltage-gated ion channel activity involved in regulation of presynaptic membrane potential

PMID:25556795[2]

ECO:0001225

knockout evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0098688

parallel fiber to Purkinje cell synapse

PMID:25556795[2]

ECO:0006063

over expression analysis evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0098688

parallel fiber to Purkinje cell synapse

PMID:25556795[2]

ECO:0006039

genetically encoded fluorescent electrophysiology assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0098688

parallel fiber to Purkinje cell synapse

PMID:25556795[2]

ECO:0006013

patch-clamp recording evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0098688

parallel fiber to Purkinje cell synapse

PMID:25556795[2]

ECO:0001225

knockout evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1341721
MGI:MGI:1341722
PANTHER:PTN000025350
RGD:68398
UniProtKB:O18965
UniProtKB:O95259
UniProtKB:Q12809

P

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1341722
PANTHER:PTN000025350
RGD:621414
UniProtKB:Q12809

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1341721
PANTHER:PTN000025350
RGD:620304
RGD:621414
RGD:68398
UniProtKB:O18965
UniProtKB:O95259
ZFIN:ZDB-GENE-070912-23

C

Seeded From UniProt

complete

enables

GO:0005249

voltage-gated potassium channel activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0000535
MGI:MGI:1341722
PANTHER:PTN000025350
RGD:2549
RGD:620304
RGD:621112
RGD:621414
UniProtKB:O18965
UniProtKB:Q12809
ZFIN:ZDB-GENE-040702-5
ZFIN:ZDB-GENE-061226-1
ZFIN:ZDB-GENE-070912-23
ZFIN:ZDB-GENE-121128-4

F

Seeded From UniProt

complete

enables

GO:1902936

phosphatidylinositol bisphosphate binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

F

Seeded From UniProt

complete

part_of

GO:0099056

integral component of presynaptic membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

enables

GO:0071889

14-3-3 protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071805

potassium ion transmembrane transport

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071805

potassium ion transmembrane transport

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071277

cellular response to calcium ion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0071277

cellular response to calcium ion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

P

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0048015

phosphatidylinositol-mediated signaling

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

P

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

F

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

enables

GO:0044325

ion channel binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

F

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

C

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

F

Seeded From UniProt

complete

part_of

GO:0042734

presynaptic membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042127

regulation of cell population proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

P

Seeded From UniProt

complete

part_of

GO:0034705

potassium channel complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0034220

ion transmembrane transport

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

P

Seeded From UniProt

complete

part_of

GO:0031901

early endosome membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

C

Seeded From UniProt

complete

part_of

GO:0030673

axolemma

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

F

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

part_of

GO:0008076

voltage-gated potassium channel complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

C

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

C

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

part_of

GO:0005637

nuclear inner membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

C

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

F

Seeded From UniProt

complete

enables

GO:0005251

delayed rectifier potassium channel activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95259

F

Seeded From UniProt

complete

enables

GO:0005251

delayed rectifier potassium channel activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001964

startle response

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68398

P

Seeded From UniProt

complete

involved_in

GO:0099505

regulation of presynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0099508

P

Seeded From UniProt

complete

involved_in

GO:0099505

regulation of presynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0099508

P

Seeded From UniProt

complete

involved_in

GO:0099505

regulation of presynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0099508

P

Seeded From UniProt

complete

involved_in

GO:0099505

regulation of presynaptic membrane potential

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0099508

P

Seeded From UniProt

complete

enables

GO:0005216

ion channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005821

F

Seeded From UniProt

complete

enables

GO:0005249

voltage-gated potassium channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003938
InterPro:IPR003949
InterPro:IPR030170

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030170

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005821

P

Seeded From UniProt

complete

involved_in

GO:0006813

potassium ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003938
InterPro:IPR003949

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003938
InterPro:IPR003949
InterPro:IPR005821

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005821

P

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030170

P

Seeded From UniProt

complete

involved_in

GO:0034765

regulation of ion transmembrane transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0851

P

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0112

F

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

enables

GO:0008289

lipid binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0446

F

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628

C

Seeded From UniProt

complete

part_of

GO:0005768

endosome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0967

C

Seeded From UniProt

complete

involved_in

GO:0071805

potassium ion transmembrane transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0631

P

Seeded From UniProt

complete

enables

GO:0005244

voltage-gated ion channel activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0851

F

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

enables

GO:0005267

potassium channel activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0631

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0006813

potassium ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0633

P

Seeded From UniProt

complete

part_of

GO:0005637

nuclear inner membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0179

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0283

C

Seeded From UniProt

complete

part_of

GO:0042734

presynaptic membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0222

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0297

C

Seeded From UniProt

complete

part_of

GO:0031901

early endosome membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0093

C

Seeded From UniProt

complete

part_of

GO:0043204

perikaryon

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0197

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0279

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Brelidze, TI et al. (2009) Absence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methods. J. Biol. Chem. 284 27989-97 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 Mortensen, LS et al. (2015) KV 10.1 opposes activity-dependent increase in Ca²⁺ influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse. J. Physiol. (Lond.) 593 181-96 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page