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MOUSE:KCC2G

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Camk2g
Protein Name(s) Calcium/calmodulin-dependent protein kinase type II subunit gamma

CaM kinase II subunit gamma CaMK-II subunit gamma

External Links
UniProt Q923T9
EMBL AF395884
AK154764
BC019162
BC025597
CCDS CCDS26855.1
CCDS26856.1
CCDS26857.1
RefSeq NP_001034227.1
NP_001034228.1
NP_848712.2
UniGene Mm.235182
ProteinModelPortal Q923T9
SMR Q923T9
BioGrid 198463
IntAct Q923T9
MINT MINT-4099582
STRING 10090.ENSMUSP00000071720
PhosphoSite Q923T9
MaxQB Q923T9
PRIDE Q923T9
Ensembl ENSMUST00000071816
ENSMUST00000080440
ENSMUST00000100837
GeneID 12325
KEGG mmu:12325
UCSC uc007skt.1
uc007sku.1
CTD 818
MGI MGI:88259
GeneTree ENSGT00760000118944
HOGENOM HOG000233016
HOVERGEN HBG108055
InParanoid Q923T9
KO K04515
OMA RDCIPSV
OrthoDB EOG7ZD1VM
PhylomeDB Q923T9
TreeFam TF315229
BRENDA 2.7.11.17
Reactome REACT_198244
REACT_198246
REACT_198248
REACT_198660
REACT_213550
REACT_258217
ChiTaRS Camk2g
NextBio 280908
PRO PR:Q923T9
Proteomes UP000000589
Bgee Q923T9
ExpressionAtlas Q923T9
Genevestigator Q923T9
GO GO:0097481
GO:0033017
GO:0005524
GO:0004683
GO:0004674
GO:0006816
GO:0030154
GO:0000082
GO:0007399
GO:0046777
GO:1901897
InterPro IPR020636
IPR013543
IPR011009
IPR000719
IPR017441
IPR002290
IPR008271
PANTHER PTHR24347
Pfam PF08332
PF00069
SMART SM00220
SUPFAM SSF56112
PROSITE PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1901897

regulation of relaxation of cardiac muscle

PMID:23283722[1]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:Q6PHZ2

P

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002389359
WB:WBGene00006779

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1341265
PANTHER:PTN002389359
RGD:2263

C

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88256
PANTHER:PTN002389359
UniProtKB:Q13557
UniProtKB:Q9UQM7

F

Seeded From UniProt

complete

enables

GO:0004683

calmodulin-dependent protein kinase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0264607
MGI:MGI:88256
MGI:MGI:88257
PANTHER:PTN002389359
RGD:2261
RGD:2262
RGD:2263
RGD:621802
UniProtKB:Q13557
UniProtKB:Q9UQM7
WB:WBGene00006779

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1903076

regulation of protein localization to plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621802

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051259

protein complex oligomerization

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13555

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046777

protein autophosphorylation

PMID:12660151[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046777

protein autophosphorylation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621802

P

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13555

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q13555

F

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:17114649[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006979

response to oxidative stress

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621802

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006816

calcium ion transport

PMID:12660151[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004683

calmodulin-dependent protein kinase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621802

F

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

PMID:12660151[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001666

response to hypoxia

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621802

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0000082

G1/S transition of mitotic cell cycle

PMID:12660151[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271

F

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039071

F

Seeded From UniProt

complete

enables

GO:0004683

calmodulin-dependent protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013543
InterPro:IPR039071

F

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013543

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271
InterPro:IPR013543

P

Seeded From UniProt

complete

enables

GO:0004683

calmodulin-dependent protein kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.11.17

F

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0016529

sarcoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0703

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0112

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

part_of

GO:0033017

sarcoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0241

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Hamdani, N et al. (2013) Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation. Circ. Res. 112 664-74 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Afroze, T et al. (2003) Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle. Am. J. Physiol., Cell Physiol. 285 C88-95 PubMed GONUTS page
  4. Munton, RP et al. (2007) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol. Cell Proteomics 6 283-93 PubMed GONUTS page