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MOUSE:KC1D
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Csnk1d (synonyms: Hckid) | |
Protein Name(s) | Casein kinase I isoform delta
CKI-delta CKId Tau-protein kinase CSNK1D | |
External Links | ||
UniProt | Q9DC28 | |
EMBL | AK004606 AK088642 AK152721 AK157812 BC004604 | |
CCDS | CCDS25762.1 CCDS25763.1 | |
PIR | S47616 | |
RefSeq | NP_620690.1 | |
UniGene | Mm.216227 | |
PDB | 4JJR | |
PDBsum | 4JJR | |
ProteinModelPortal | Q9DC28 | |
SMR | Q9DC28 | |
BioGrid | 222545 | |
DIP | DIP-47809N | |
IntAct | Q9DC28 | |
STRING | 10090.ENSMUSP00000094305 | |
BindingDB | Q9DC28 | |
PhosphoSite | Q9DC28 | |
MaxQB | Q9DC28 | |
PaxDb | Q9DC28 | |
PRIDE | Q9DC28 | |
Ensembl | ENSMUST00000018274 ENSMUST00000070575 | |
GeneID | 104318 | |
KEGG | mmu:104318 | |
UCSC | uc007mvb.1 | |
CTD | 1453 | |
MGI | MGI:1355272 | |
eggNOG | COG0515 | |
GeneTree | ENSGT00760000119040 | |
HOGENOM | HOG000182055 | |
HOVERGEN | HBG000176 | |
InParanoid | Q9DC28 | |
KO | K08959 | |
OMA | PTSHAAN | |
OrthoDB | EOG7CZK5W | |
TreeFam | TF300544 | |
Reactome | REACT_196635 REACT_241925 REACT_243078 REACT_244487 REACT_245720 REACT_24972 | |
ChiTaRS | Csnk1d | |
NextBio | 356922 | |
PRO | PR:Q9DC28 | |
Proteomes | UP000000589 | |
Bgee | Q9DC28 | |
CleanEx | MM_CSNK1D | |
ExpressionAtlas | Q9DC28 | |
Genevestigator | Q9DC28 | |
GO | GO:0005813 GO:0005829 GO:0005794 GO:0005654 GO:0005634 GO:0048471 GO:0005886 GO:0005876 GO:0005524 GO:0042277 GO:0004672 GO:0004674 GO:0050321 GO:0032922 GO:0090263 GO:0032436 GO:0001934 GO:0006468 GO:0042752 GO:0051225 GO:0016055 | |
InterPro | IPR011009 IPR000719 IPR017441 IPR008271 | |
Pfam | PF00069 | |
SUPFAM | SSF56112 | |
PROSITE | PS00107 PS50011 PS00108 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:1905426 |
positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation |
ECO:0000305 |
curator inference used in manual assertion |
GO:0006468,GO:2000052 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:2000052 |
positive regulation of non-canonical Wnt signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030177 |
positive regulation of Wnt signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
occurs_in:(CL:0000700) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
F |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
|
Seeded From UniProt |
complete | ||
involved_in |
GO:0042752 |
regulation of circadian rhythm |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0042752 |
regulation of circadian rhythm |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032922 |
circadian regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032922 |
circadian regulation of gene expression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032436 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:1905515 |
non-motile cilium assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1355272 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090263 |
positive regulation of canonical Wnt signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002629128 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051225 |
spindle assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002629128 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042752 |
regulation of circadian rhythm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1355272 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032436 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1355272 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018107 |
peptidyl-threonine phosphorylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0027889 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018105 |
peptidyl-serine phosphorylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2155779 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005876 |
spindle microtubule |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002629128 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002413 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002413 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002413 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1905515 |
non-motile cilium assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(CL:1001225) |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1905515 |
non-motile cilium assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3849883 |
P |
occurs_in:(CL:0000057)|occurs_in:(EMAPA:17168) |
Seeded From UniProt |
complete | |
acts_upstream_of_or_within |
GO:1905515 |
non-motile cilium assembly |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0090263 |
positive regulation of canonical Wnt signaling pathway |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0071539 |
protein localization to centrosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0061512 |
protein localization to cilium |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0051225 |
spindle assembly |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:71031 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:71031 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0034067 |
protein localization to Golgi apparatus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0018105 |
peptidyl-serine phosphorylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:71031 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0007030 |
Golgi organization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0007020 |
microtubule nucleation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006468 |
protein phosphorylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006468 |
protein phosphorylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:71031 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:71031 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005876 |
spindle microtubule |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005819 |
spindle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005813 |
centrosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005813 |
centrosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:71031 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:71031 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:71031 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0001934 |
positive regulation of protein phosphorylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1990090 |
cellular response to nerve growth factor stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0016301 |
kinase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005813 |
centrosome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q06486 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0050321 |
tau-protein kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
Reactome:R-MMU-549498 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-MMU-549498 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048511 |
rhythmic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016055 |
Wnt signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005815 |
microtubule organizing center |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005819 |
spindle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Bryja, V et al. (2007) Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J. Cell. Sci. 120 586-95 PubMed GONUTS page
- ↑ 2.0 2.1 Bryja, V et al. (2007) Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell. Signal. 19 610-6 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Lee, HM et al. (2011) The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1. Proc. Natl. Acad. Sci. U.S.A. 108 16451-6 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Etchegaray, JP et al. (2009) Casein kinase 1 delta regulates the pace of the mammalian circadian clock. Mol. Cell. Biol. 29 3853-66 PubMed GONUTS page
- ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 6.0 6.1 Greer, YE et al. (2014) Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis. Mol. Biol. Cell 25 1629-40 PubMed GONUTS page
c
m
n
p
- GO:0018105 ! peptidyl-serine phosphorylation
- GO:0018107 ! peptidyl-threonine phosphorylation
- GO:0048471 ! perinuclear region of cytoplasm
- GO:0016310 ! phosphorylation
- GO:0005886 ! plasma membrane
- GO:2000052 ! positive regulation of non-canonical Wnt signaling pathway
- GO:0090263 ! positive regulation of canonical Wnt signaling pathway
- GO:0032436 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process
- GO:0001934 ! positive regulation of protein phosphorylation
- GO:0030177 ! positive regulation of Wnt signaling pathway
- GO:0004672 ! protein kinase activity
- GO:0034067 ! protein localization to Golgi apparatus
- GO:0061512 ! protein localization to cilium
- GO:0071539 ! protein localization to centrosome
- GO:0006468 ! protein phosphorylation
- GO:0004674 ! protein serine/threonine kinase activity