MOUSE:IQGA1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Iqgap1
Protein Name(s)	Ras GTPase-activating-like protein IQGAP1
External Links
UniProt	Q9JKF1
EMBL	AF240630 AC109257 AC127594 CH466543
CCDS	CCDS40001.1
RefSeq	NP_057930.2
UniGene	Mm.207619
ProteinModelPortal	Q9JKF1
SMR	Q9JKF1
IntAct	Q9JKF1
MINT	MINT-1563339
PhosphoSite	Q9JKF1
MaxQB	Q9JKF1
PaxDb	Q9JKF1
PRIDE	Q9JKF1
Ensembl	ENSMUST00000167377
GeneID	29875
KEGG	mmu:29875
UCSC	uc009ibc.2
CTD	8826
MGI	MGI:1352757
eggNOG	COG5261
GeneTree	ENSGT00600000084379
HOVERGEN	HBG052143
InParanoid	Q9JKF1
KO	K16848
OMA	QDILYQA
OrthoDB	EOG7FNC6M
TreeFam	TF313078
Reactome	REACT_257032
ChiTaRS	Iqgap1
NextBio	307110
PRO	PR:Q9JKF1
Proteomes	UP000000589
CleanEx	MM_IQGAP1
ExpressionAtlas	Q9JKF1
Genevestigator	Q9JKF1
GO	GO:0030424 GO:0031252 GO:0005911 GO:0005737 GO:0036464 GO:0070062 GO:0031234 GO:0030426 GO:0016328 GO:0016020 GO:0005874 GO:0030496 GO:0043005 GO:0005634 GO:0030529 GO:0036057 GO:0005547 GO:0043539 GO:0048365 GO:0005099 GO:0017048 GO:0071277 GO:0071364 GO:0044344 GO:0036120 GO:0007173 GO:0008543 GO:0072015 GO:0035305 GO:0048008 GO:0045860 GO:0001817 GO:0007264
Gene3D	1.10.418.10 1.10.506.10 4.10.270.10
InterPro	IPR001715 IPR000048 IPR027401 IPR027417 IPR000593 IPR023152 IPR001936 IPR008936 IPR001202
Pfam	PF00307 PF00612 PF00616 PF03836
SMART	SM00033 SM00015 SM00323
SUPFAM	SSF47576 SSF48350 SSF52540
PROSITE	PS50021 PS50096 PS00509 PS50018 PS01159

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
involved_in	GO:0007346	regulation of mitotic cell cycle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P46940	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:20883816^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:G3V7Q7	C		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:G3V7Q7	C		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:G3V7Q7	C		Seeded From UniProt	complete
colocalizes_with	GO:0015630	microtubule cytoskeleton	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:G3V7Q7	C	part_of:(CL:0000540)	Seeded From UniProt	complete
colocalizes_with	GO:0015629	actin cytoskeleton	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:G3V7Q7	C	part_of:(CL:0000540)	Seeded From UniProt	complete
involved_in	GO:0044344	cellular response to fibroblast growth factor stimulus	PMID:17563371^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008543	fibroblast growth factor receptor signaling pathway	PMID:17563371^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048008	platelet-derived growth factor receptor signaling pathway	PMID:17563371^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0036120	cellular response to platelet-derived growth factor stimulus	PMID:17563371^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071364	cellular response to epidermal growth factor stimulus	PMID:17563371^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007173	epidermal growth factor receptor signaling pathway	PMID:17563371^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045860	positive regulation of protein kinase activity	PMID:17563371^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_regulation_target:(UniProtKB:P28028) part_of:(GO:0007173)\|has_regulation_target(UniProtKB:P15056) part_of:(GO:0071364)	Seeded From UniProt	complete
involved_in	GO:0072015	glomerular visceral epithelial cell development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:B5DFH1	P		Seeded From UniProt	complete
part_of	GO:0036057	slit diaphragm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:B5DFH1	C		Seeded From UniProt	complete
part_of	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
enables	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
part_of	GO:1990904	ribonucleoprotein complex	PMID:21709260^[3]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:2444126	C		Seeded From UniProt	complete
part_of	GO:1990904	ribonucleoprotein complex	PMID:21709260^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1990138	neuron projection extension	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1903829	positive regulation of cellular protein localization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1900006	positive regulation of dendrite development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071364	cellular response to epidermal growth factor stimulus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071277	cellular response to calcium ion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	P		Seeded From UniProt	complete
enables	GO:0060090	molecular adaptor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051894	positive regulation of focal adhesion assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	P		Seeded From UniProt	complete
enables	GO:0051019	mitogen-activated protein kinase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	F		Seeded From UniProt	complete
enables	GO:0048365	Rac GTPase binding	PMID:18604197^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P63001	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045860	positive regulation of protein kinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	F		Seeded From UniProt	complete
enables	GO:0044548	S100 protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
enables	GO:0043539	protein serine/threonine kinase activator activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043406	positive regulation of MAP kinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	P		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:16369480^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:109520	C	part_of:(CL:0000540)	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
part_of	GO:0036464	cytoplasmic ribonucleoprotein granule	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035305	negative regulation of dephosphorylation	PMID:21709260^[3]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:2444126	P		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
enables	GO:0031267	small GTPase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
part_of	GO:0031252	cell leading edge	PMID:16369480^[5]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:109520	C	part_of:(CL:0000540)	Seeded From UniProt	complete
part_of	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
enables	GO:0019903	protein phosphatase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
enables	GO:0017048	Rho GTPase binding	PMID:18604197^[4]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9QUI0	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016477	cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	P		Seeded From UniProt	complete
part_of	GO:0016328	lateral plasma membrane	PMID:18604197^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002327)	Seeded From UniProt	complete
colocalizes_with	GO:0015630	microtubule cytoskeleton	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
colocalizes_with	GO:0015629	actin cytoskeleton	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007346	regulation of mitotic cell cycle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007173	epidermal growth factor receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	P		Seeded From UniProt	complete
colocalizes_with	GO:0005925	focal adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
part_of	GO:0005911	cell-cell junction	PMID:18604197^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002327)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
part_of	GO:0005874	microtubule	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:18604197^[4]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002327)	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:14516655^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1311884	C		Seeded From UniProt	complete
enables	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
enables	GO:0005516	calmodulin binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001817	regulation of cytokine production	PMID:21709260^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0001726	ruffle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P46940	C		Seeded From UniProt	complete
involved_in	GO:1990776	response to angiotensin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	P		Seeded From UniProt	complete
involved_in	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	P		Seeded From UniProt	complete
involved_in	GO:1903829	positive regulation of cellular protein localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	P		Seeded From UniProt	complete
involved_in	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	P		Seeded From UniProt	complete
involved_in	GO:1900006	positive regulation of dendrite development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	P		Seeded From UniProt	complete
involved_in	GO:0051894	positive regulation of focal adhesion assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	P		Seeded From UniProt	complete
enables	GO:0051019	mitogen-activated protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	F		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	F		Seeded From UniProt	complete
involved_in	GO:0043406	positive regulation of MAP kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	P		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
part_of	GO:0015630	microtubule cytoskeleton	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
part_of	GO:0015629	actin cytoskeleton	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
part_of	GO:0005925	focal adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V7Q7 ensembl:ENSRNOP00000018021	C		Seeded From UniProt	complete
involved_in	GO:1990138	neuron projection extension	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	P		Seeded From UniProt	complete
involved_in	GO:0071364	cellular response to epidermal growth factor stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	P		Seeded From UniProt	complete
involved_in	GO:0071277	cellular response to calcium ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	P		Seeded From UniProt	complete
enables	GO:0060090	molecular adaptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
involved_in	GO:0045860	positive regulation of protein kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	P		Seeded From UniProt	complete
enables	GO:0044548	S100 protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
enables	GO:0043539	protein serine/threonine kinase activator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
part_of	GO:0036464	cytoplasmic ribonucleoprotein granule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	C		Seeded From UniProt	complete
enables	GO:0031267	small GTPase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
part_of	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	C		Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	C		Seeded From UniProt	complete
enables	GO:0019904	protein domain specific binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
enables	GO:0019903	protein phosphatase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
involved_in	GO:0016477	cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	P		Seeded From UniProt	complete
involved_in	GO:0007346	regulation of mitotic cell cycle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	P		Seeded From UniProt	complete
involved_in	GO:0007173	epidermal growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	C		Seeded From UniProt	complete
part_of	GO:0005874	microtubule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	C		Seeded From UniProt	complete
enables	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
enables	GO:0005516	calmodulin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	F		Seeded From UniProt	complete
part_of	GO:0001726	ruffle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P46940 ensembl:ENSP00000268182	C		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008936	P		Seeded From UniProt	complete
involved_in	GO:0043087	regulation of GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001936 InterPro:IPR023152	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
enables	GO:0005516	calmodulin binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0112	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Johnson, M et al. (2011) IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest. Int. J. Biochem. Cell Biol. 43 65-73 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Ren, JG et al. (2007) IQGAP1 modulates activation of B-Raf. Proc. Natl. Acad. Sci. U.S.A. 104 10465-9 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Sharma, S et al. (2011) Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. Proc. Natl. Acad. Sci. U.S.A. 108 11381-6 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 Nojima, H et al. (2008) IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade. Nat. Cell Biol. 10 971-8 PubMed GONUTS page
↑ ^5.0 ^5.1 Kholmanskikh, SS et al. (2006) Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility. Nat. Neurosci. 9 50-7 PubMed GONUTS page
↑ Natale, DR & Watson, AJ (2002) Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Mech. Dev. 119 Suppl 1 S21-6 PubMed GONUTS page

[PMID:20883816-1] Johnson, M et al. (2011) IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest. Int. J. Biochem. Cell Biol. 43 65-73 PubMed GONUTS page

[PMID:17563371-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 Ren, JG et al. (2007) IQGAP1 modulates activation of B-Raf. Proc. Natl. Acad. Sci. U.S.A. 104 10465-9 PubMed GONUTS page

[PMID:21709260-3] 3.0 ^3.1 ^3.2 ^3.3 Sharma, S et al. (2011) Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. Proc. Natl. Acad. Sci. U.S.A. 108 11381-6 PubMed GONUTS page

[PMID:18604197-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 Nojima, H et al. (2008) IQGAP3 regulates cell proliferation through the Ras/ERK signalling cascade. Nat. Cell Biol. 10 971-8 PubMed GONUTS page

[PMID:16369480-5] 5.0 ^5.1 Kholmanskikh, SS et al. (2006) Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility. Nat. Neurosci. 9 50-7 PubMed GONUTS page

[PMID:14516655-6] Natale, DR & Watson, AJ (2002) Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Mech. Dev. 119 Suppl 1 S21-6 PubMed GONUTS page

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MOUSE:IQGA1

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