MOUSE:HIP1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Hip1 (ECO:0000312 with MGI:MGI:1099804) (synonyms: Kiaa4113 (ECO:0000312 with EMBL:BAD90367.1))
Protein Name(s)	Huntingtin-interacting protein 1 (ECO:0000250 with UniProtKB:O00291) HIP-1 Huntingtin-interacting protein I HIP-I (ECO:0000250 with UniProtKB:O00291)
External Links
UniProt	Q8VD75
EMBL	BC017516 AK166346 AK220182
CCDS	CCDS51663.1
RefSeq	NP_666113.2
UniGene	Mm.280805
ProteinModelPortal	Q8VD75
SMR	Q8VD75
BioGrid	229599
STRING	10090.ENSMUSP00000059033
PhosphoSite	Q8VD75
MaxQB	Q8VD75
PaxDb	Q8VD75
PRIDE	Q8VD75
Ensembl	ENSMUST00000060311
GeneID	215114
KEGG	mmu:215114
UCSC	uc008zyj.2
CTD	3092
MGI	MGI:1099804
eggNOG	NOG280957
GeneTree	ENSGT00550000074542
HOGENOM	HOG000020612
HOVERGEN	HBG005968
InParanoid	Q8VD75
KO	K04559
OMA	VQGRGKF
OrthoDB	EOG72JWFF
PhylomeDB	Q8VD75
TreeFam	TF316860
ChiTaRS	Hip1
NextBio	374616
PRO	PR:Q8VD75
Proteomes	UP000000589
Bgee	Q8VD75
Genevestigator	Q8VD75
GO	GO:0030136 GO:0030665 GO:0005794 GO:0005634 GO:0030276 GO:0035091 GO:0006919 GO:0006915 GO:0097190 GO:0030154 GO:0048268 GO:0006897 GO:0048260 GO:0042981 GO:0006355 GO:0006351
Gene3D	1.20.1410.10 1.25.40.90
InterPro	IPR011417 IPR013809 IPR008942 IPR002558 IPR030224
PANTHER	PTHR10407
Pfam	PF07651 PF01608
ProDom	PD011820
SMART	SM00273 SM00307
SUPFAM	SSF109885 SSF48464
PROSITE	PS50942 PS50945

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0048260	positive regulation of receptor-mediated endocytosis	PMID:11577110^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0035091	phosphatidylinositol binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	PMID:11604514^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0098890	extrinsic component of postsynaptic membrane	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045171 RGD:620305	C	Seeded From UniProt	complete
part_of	GO:0098793	presynapse	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045171 RGD:620305 UniProtKB:O00291	C	Seeded From UniProt	complete
enables	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045135 UniProtKB:O00291 UniProtKB:O75146	F	Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1352504 PANTHER:PTN000045135 UniProtKB:O00291 UniProtKB:O75146	F	Seeded From UniProt	complete
involved_in	GO:0048268	clathrin coat assembly	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1352504 PANTHER:PTN000045135 RGD:620305 UniProtKB:O00291	P	Seeded From UniProt	complete
involved_in	GO:0048260	positive regulation of receptor-mediated endocytosis	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1099804 PANTHER:PTN000045135 UniProtKB:O00291	P	Seeded From UniProt	complete
enables	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045135 UniProtKB:O00291 UniProtKB:O75146	F	Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045135 UniProtKB:O00291 UniProtKB:O75146	C	Seeded From UniProt	complete
enables	GO:0035615	clathrin adaptor activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1352504 PANTHER:PTN000045135	F	Seeded From UniProt	complete
enables	GO:0035091	phosphatidylinositol binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045135 UniProtKB:O00291 UniProtKB:O75146	F	Seeded From UniProt	complete
enables	GO:0032051	clathrin light chain binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1352504 PANTHER:PTN000045135 UniProtKB:O00291	F	Seeded From UniProt	complete
part_of	GO:0030479	actin cortical patch	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045135 PomBase:SPAC688.11 SGD:S000005187 UniProtKB:A0A1D8PRF5	C	Seeded From UniProt	complete
enables	GO:0030276	clathrin binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1352504 PANTHER:PTN000045135 RGD:620305 UniProtKB:O00291 UniProtKB:O75146	F	Seeded From UniProt	complete
colocalizes_with	GO:0030136	clathrin-coated vesicle	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1352504 PANTHER:PTN000045135 RGD:620305 UniProtKB:O00291 UniProtKB:O75146 dictyBase:DDB_G0285703	C	Seeded From UniProt	complete
colocalizes_with	GO:0030122	AP-2 adaptor complex	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045135 UniProtKB:O00291	C	Seeded From UniProt	complete
involved_in	GO:0007015	actin filament organization	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045135 SGD:S000005187 UniProtKB:A0A1D8PRF5	P	Seeded From UniProt	complete
involved_in	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045138 UniProtKB:O00291 UniProtKB:O75146	P	Seeded From UniProt	complete
colocalizes_with	GO:0005737	cytoplasm	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000045135 UniProtKB:O00291 dictyBase:DDB_G0285703	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	C	Seeded From UniProt	complete
part_of	GO:0098890	extrinsic component of postsynaptic membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	C	Seeded From UniProt	complete
part_of	GO:0098888	extrinsic component of presynaptic membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	C	Seeded From UniProt	complete
part_of	GO:0098794	postsynapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	C	Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	C	Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0097190	apoptotic signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
enables	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050821	protein stabilization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048268	clathrin coat assembly	PMID:11577110^[1]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048268	clathrin coat assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048268	clathrin coat assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048260	positive regulation of receptor-mediated endocytosis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	C	Seeded From UniProt	complete
enables	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042981	regulation of apoptotic process	PMID:11788820^[4]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
enables	GO:0035612	AP-2 adaptor complex binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
enables	GO:0035091	phosphatidylinositol binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
enables	GO:0032266	phosphatidylinositol-3-phosphate binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
enables	GO:0032051	clathrin light chain binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
part_of	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	C	Seeded From UniProt	complete
enables	GO:0030276	clathrin binding	PMID:11577110^[1]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
enables	GO:0030276	clathrin binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	F	Seeded From UniProt	complete
enables	GO:0030276	clathrin binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	F	Seeded From UniProt	complete
enables	GO:0030276	clathrin binding	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	EMBL:AF388529	F	Seeded From UniProt	complete
part_of	GO:0030136	clathrin-coated vesicle	PMID:11577110^[1]	ECO:0000266	sequence orthology evidence used in manual assertion	EMBL:AF388529	C	Seeded From UniProt	complete
part_of	GO:0030136	clathrin-coated vesicle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	C	Seeded From UniProt	complete
part_of	GO:0030136	clathrin-coated vesicle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620305	C	Seeded From UniProt	complete
colocalizes_with	GO:0030122	AP-2 adaptor complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	PMID:11788820^[4]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006915	apoptotic process	PMID:11788820^[4]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	P	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	PMID:11788820^[4]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O00291	C	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	C	Seeded From UniProt	complete
part_of	GO:0098890	extrinsic component of postsynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	C	Seeded From UniProt	complete
part_of	GO:0098888	extrinsic component of presynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	C	Seeded From UniProt	complete
part_of	GO:0098794	postsynapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	C	Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	C	Seeded From UniProt	complete
involved_in	GO:0048268	clathrin coat assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	P	Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	C	Seeded From UniProt	complete
part_of	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	C	Seeded From UniProt	complete
enables	GO:0030276	clathrin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	F	Seeded From UniProt	complete
part_of	GO:0030136	clathrin-coated vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:G3V8Y8 ensembl:ENSRNOP00000031153	C	Seeded From UniProt	complete
involved_in	GO:2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	C	Seeded From UniProt	complete
involved_in	GO:0097190	apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
enables	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
enables	GO:0051015	actin filament binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
involved_in	GO:0050821	protein stabilization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
involved_in	GO:0048268	clathrin coat assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
involved_in	GO:0048260	positive regulation of receptor-mediated endocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
involved_in	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
enables	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	C	Seeded From UniProt	complete
involved_in	GO:0042981	regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
enables	GO:0035612	AP-2 adaptor complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
enables	GO:0035091	phosphatidylinositol binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
enables	GO:0032266	phosphatidylinositol-3-phosphate binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
enables	GO:0032051	clathrin light chain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
enables	GO:0030276	clathrin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	F	Seeded From UniProt	complete
part_of	GO:0030136	clathrin-coated vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	C	Seeded From UniProt	complete
part_of	GO:0030122	AP-2 adaptor complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	C	Seeded From UniProt	complete
involved_in	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
involved_in	GO:0006915	apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	P	Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O00291 ensembl:ENSP00000336747	C	Seeded From UniProt	complete
enables	GO:0003779	actin binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002558 InterPro:IPR035964	F	Seeded From UniProt	complete
enables	GO:0005543	phospholipid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011417	F	Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030224	P	Seeded From UniProt	complete
involved_in	GO:0006915	apoptotic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030554	P	Seeded From UniProt	complete
part_of	GO:0030136	clathrin-coated vesicle	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030554	C	Seeded From UniProt	complete
enables	GO:0030276	clathrin binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030224 InterPro:IPR030554	F	Seeded From UniProt	complete
enables	GO:0035091	phosphatidylinositol binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030554	F	Seeded From UniProt	complete
involved_in	GO:0048268	clathrin coat assembly	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030554	P	Seeded From UniProt	complete
involved_in	GO:0072583	clathrin-dependent endocytosis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030554	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
involved_in	GO:0006897	endocytosis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0254	P	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C	Seeded From UniProt	complete
involved_in	GO:0006915	apoptotic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0053	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
enables	GO:0003779	actin binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0009	F	Seeded From UniProt	complete
part_of	GO:0012505	endomembrane system	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0147	C	Seeded From UniProt	complete
part_of	GO:0030665	clathrin-coated vesicle membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0071	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Mishra, SK et al. (2001) Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins. J. Biol. Chem. 276 46230-6 PubMed GONUTS page
↑ Rao, DS et al. (2001) Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors. Mol. Cell. Biol. 21 7796-806 PubMed GONUTS page
↑ ^3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Gervais, FG et al. (2002) Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat. Cell Biol. 4 95-105 PubMed GONUTS page

[PMID:11577110-1] 1.0 ^1.1 ^1.2 ^1.3 Mishra, SK et al. (2001) Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins. J. Biol. Chem. 276 46230-6 PubMed GONUTS page

[PMID:11604514-2] Rao, DS et al. (2001) Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors. Mol. Cell. Biol. 21 7796-806 PubMed GONUTS page

[PMID:21873635-3] 3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 ^3.11 ^3.12 ^3.13 ^3.14 ^3.15 ^3.16 ^3.17 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11788820-4] 4.0 ^4.1 ^4.2 ^4.3 Gervais, FG et al. (2002) Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat. Cell Biol. 4 95-105 PubMed GONUTS page

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