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MOUSE:GPBAR
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Gpbar1 (synonyms: Tgr5) | |
| Protein Name(s) | G-protein coupled bile acid receptor 1
Membrane-type receptor for bile acids M-BAR | |
| External Links | ||
| UniProt | Q80SS6 | |
| EMBL | AB086171 AB089308 | |
| CCDS | CCDS15042.1 | |
| RefSeq | NP_778150.1 | |
| UniGene | Mm.246587 | |
| ProteinModelPortal | Q80SS6 | |
| SMR | Q80SS6 | |
| BindingDB | Q80SS6 | |
| ChEMBL | CHEMBL1255150 | |
| GuidetoPHARMACOLOGY | 37 | |
| PRIDE | Q80SS6 | |
| Ensembl | ENSMUST00000077985 | |
| GeneID | 227289 | |
| KEGG | mmu:227289 | |
| UCSC | uc007blq.1 | |
| CTD | 151306 | |
| MGI | MGI:2653863 | |
| eggNOG | NOG70795 | |
| GeneTree | ENSGT00390000010256 | |
| HOGENOM | HOG000065748 | |
| HOVERGEN | HBG081571 | |
| InParanoid | Q80SS6 | |
| KO | K08400 | |
| OMA | WGPYVAT | |
| OrthoDB | EOG7MWGXP | |
| PhylomeDB | Q80SS6 | |
| TreeFam | TF333321 | |
| Reactome | REACT_242871 REACT_261161 | |
| NextBio | 378532 | |
| PRO | PR:Q80SS6 | |
| Proteomes | UP000000589 | |
| CleanEx | MM_GPBAR1 | |
| ExpressionAtlas | Q80SS6 | |
| Genevestigator | Q80SS6 | |
| GO | GO:0005737 GO:0016021 GO:0005886 GO:0038181 GO:0004930 | |
| InterPro | IPR000276 IPR017452 | |
| Pfam | PF00001 | |
| PRINTS | PR00237 | |
| PROSITE | PS50262 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:2000810 |
regulation of tight junction assembly |
ECO:0000315 |
P |
Based on Figure 1 A, B and C |
complete | |||||
|
involved_in |
GO:2000810 |
regulation of bicellular tight junction assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0038181 |
bile acid receptor activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
EMBL:AB086170 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:631400 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0038183 |
bile acid signaling pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0038181 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0038183 |
bile acid signaling pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0038181 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q80T02 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0038181 |
bile acid receptor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8TDU6 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8TDU6 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8TDU6 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004930 |
G protein-coupled receptor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007186 |
G protein-coupled receptor signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Cipriani, S et al. (2011) The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis. PLoS ONE 6 e25637 PubMed GONUTS page
- ↑ Maruyama, T et al. (2002) Identification of membrane-type receptor for bile acids (M-BAR). Biochem. Biophys. Res. Commun. 298 714-9 PubMed GONUTS page
